Salmonella, the insidious contributor to gallbladder and colon cancers

Abstract

Salmonella infects hundreds of millions of people yearly, invading host cells and altering signalling pathways that can promote cancer. Owing to their biological origin, Salmonella-induced cancers may respond better to specific treatments, shedding light on different modes of bacterially driven cellular transformation and effective ways to counter them. Salmonella infections, prevalent globally, correlate with increased risk of cancer, particularly gallbladder and colon cancers. In this Comment, Stévenin and Neefjes highlight the need for further investigation into Salmonella-driven cellular transformation.