[Ocular graft versus host disease].

Die Ophthalmologie Pub Date : 2025-04-01 Epub Date: 2025-03-31 DOI:10.1007/s00347-025-02212-y
Philipp Steven, Tina Dietrich-Ntoukas
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引用次数: 0

Abstract

Ocular graft versus host disease (GVHD) following allogeneic hematopoietic stem cell transplantation (HSCT) is predominantly an inflammatory and destructive ocular surface disease with increasing incidence. It not only leads to a reduced quality-of-life but can also impair vision and in severe cases lead to blindness. The occurrence of GVHD can lead to a severe, often refractory disorders of the ocular surface, which is associated with chronic inflammation. The occurrence of corneal involvement is a major problem. The establishment of comprehensive care structures and individually adapted stage-appropriate treatment in interdisciplinary collaboration with colleagues in hemato-oncology is therefore of particular importance.

眼移植物抗宿主病。
同种异体造血干细胞移植(HSCT)后的眼移植物抗宿主病(GVHD)主要是一种发病率越来越高的炎症性和破坏性眼表疾病。它不仅会导致生活质量下降,还会损害视力,严重时还会导致失明。GVHD的发生可导致严重的,通常是难治性的眼表疾病,这与慢性炎症有关。角膜受累的发生是一个主要问题。因此,在与血液肿瘤学同事的跨学科合作中建立全面的护理结构和个别适应的适合阶段的治疗是特别重要的。
本文章由计算机程序翻译,如有差异,请以英文原文为准。
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