[Rare cause of recurrent hypoglycemia].

Abstract

Non-islet cell tumor hypoglycemia (NICTH) is a rare cause of hypoglycemia, resulting from excessive secretion of insulin-like growth factor 2 (IGF-2) or pro-IGF‑2, which leads to subsequent activation of the insulin receptor. Doege-Potter syndrome is often used synonymously with NICTH, especially in cases with fibrous primary tumors in the thorax. In the current patient, tumor progression was observed over a short period without the possibility of debulking surgery. Therefore, oral therapy with prednisolone was initiated. Treatment with diazoxide or the somatostatin analogue octreotide is not recommended for NICTH.