Pei Chen, Yueying Wang, Jinjin Yuan, Ghada Bourjeily, Chang G Park, Bingqian Zhu, Bilgay Izci-Balserak
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引用次数: 0
Abstract
Study objectives: Sleep problems are common during pregnancy. Maintaining good sleep is critical to maternal and fetal health. The objective of this study was to evaluate the effectiveness of non-pharmacological interventions in improving sleep quality and duration during pregnancy, using objective and subjective sleep measures.
Methods: This meta-analysis was conducted ensuring compliance with the Preferred Reporting Items for Systematic Reviews and Meta-Analysis guidelines. We systematically searched five major electronic databases, PubMed, Cumulative Index to Nursing and Allied Health Literature, Embase, Web of Science, and Cochrane. Only randomized-control trials of non-pharmacological interventions to improve sleep in pregnancy were included. We used random or fixed effect models and pooled estimates as standardized mean differences with 95% confidence intervals (CI). Funnel plots and sensitivity analysis were used to assess publication bias and result robustness.
Results: A total of 31 studies (N=3,307) were included. Meta-analysis revealed that non-pharmacological interventions significantly improved self-reported overall sleep quality (SMD=-0.99; 95% CI =-1.40, -0.58; I2 = 96.3%). Subgroup analysis indicated that interventions initiated in late pregnancy (SMD=-0.88; 95% CI=-1.16, -0.60; I2 =85.6%) or spanning different pregnancy stages were effective (SMD=-1.10; 95% CI=-1.97, -0.24; I2=98.1%). However, these interventions did not significantly affect sleep duration or efficiency, whether self-reported or objectively measured.
Conclusions: Non-pharmacological interventions can improve self-reported sleep quality in pregnant women. Clinicians can tailor interventions based on pregnancy period and individual needs to manage their sleep disturbances.
研究目的：睡眠问题在怀孕期间很常见。保持良好的睡眠对母婴健康至关重要。本研究的目的是评估非药物干预在改善怀孕期间睡眠质量和持续时间方面的有效性，使用客观和主观的睡眠测量。方法：本荟萃分析确保符合系统评价和荟萃分析指南的首选报告项目。我们系统地检索了5个主要的电子数据库：PubMed、护理和联合健康文献累积索引、Embase、Web of Science和Cochrane。仅纳入了改善妊娠期睡眠的非药物干预的随机对照试验。我们使用随机或固定效应模型和汇总估计作为95%置信区间（CI）的标准化平均差异。采用漏斗图和敏感性分析评估发表偏倚和结果稳健性。结果：共纳入31项研究（N= 3307）。meta分析显示，非药物干预显著改善了自我报告的整体睡眠质量(SMD=-0.99；95% ci =-1.40, -0.58；I2 = 96.3%)。亚组分析表明，干预措施始于妊娠晚期(SMD=-0.88；95% ci =-1.16, -0.60；I2 =85.6%)或跨越不同妊娠期有效(SMD=-1.10；95% ci =-1.97, -0.24；I2 = 98.1%)。然而，无论是自我报告还是客观测量，这些干预措施都没有显著影响睡眠时间或效率。结论：非药物干预可改善孕妇自我报告的睡眠质量。临床医生可以根据怀孕期间和个人需要量身定制干预措施，以管理她们的睡眠障碍。系统审查注册：Registry: PROSPERO；标识符:CRD42022372289。
期刊介绍：
Journal of Clinical Sleep Medicine focuses on clinical sleep medicine. Its emphasis is publication of papers with direct applicability and/or relevance to the clinical practice of sleep medicine. This includes clinical trials, clinical reviews, clinical commentary and debate, medical economic/practice perspectives, case series and novel/interesting case reports. In addition, the journal will publish proceedings from conferences, workshops and symposia sponsored by the American Academy of Sleep Medicine or other organizations related to improving the practice of sleep medicine.
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