Oral contraceptive pill-induced esophagitis: a rare cause of pill esophagitis in a Rwandan woman.

IF 0.5 Q3 MEDICINE, GENERAL & INTERNAL
Oxford Medical Case Reports Pub Date : 2025-03-28 eCollection Date: 2025-04-01 DOI:10.1093/omcr/omaf001
Gordon P Bensen, Matthew R Bryan, Esther Nishimwe, Bao Sean Nguyen, Kenechukwu Chudy-Onwugaje
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引用次数: 0

Abstract

We describe a case of oral contraceptive pill (OCP)-induced esophagitis in a 43-year-old Rwandan woman. She presented with epigastric and retrosternal pain and reported daily use of a combined OCP containing ethinyl estradiol and levonorgestrel. Upper endoscopy revealed a solitary, clean-based esophageal ulcer. Histopathologic evaluation excluded infectious causes, and she improved with proton pump inhibitor therapy and modification of pill consumption habits. This is the first reported case of OCP-induced esophagitis on the African continent and the fifth case overall, and it highlights the importance of awareness of this rare gastrointestinal adverse effect of a commonly used class of drugs, particularly in an area of the world that is promoting the increased uptake of female contraception as a tool for family planning.

口服避孕药引起的食管炎:一名卢旺达妇女的罕见原因。
我们描述了一例口服避孕药(OCP)引起的食管炎在一个43岁的卢旺达妇女。她表现为上腹部和胸骨后疼痛,并报告每日使用含有炔雌醇和左炔诺孕酮的联合OCP。上腔镜检查显示一孤立的清洁性食管溃疡。组织病理学检查排除了感染原因,并通过质子泵抑制剂治疗和改变服药习惯得到改善。这是非洲大陆报道的第一例ocp引起的食管炎病例,也是总体上的第5例,它强调了对这类常用药物的罕见胃肠道不良反应的认识的重要性,特别是在世界上正在促进增加女性避孕作为计划生育工具的地区。
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来源期刊
Oxford Medical Case Reports
Oxford Medical Case Reports MEDICINE, GENERAL & INTERNAL-
CiteScore
0.90
自引率
0.00%
发文量
125
审稿时长
19 weeks
期刊介绍: Oxford Medical Case Reports (OMCR) is an open access, peer-reviewed online journal publishing original and educationally valuable case reports that expand the field of medicine. The journal covers all medical specialities including cardiology, rheumatology, nephrology, oncology, neurology, and reproduction, comprising a comprehensive resource for physicians in all fields and at all stages of training. Oxford Medical Case Reports deposits all articles in PubMed Central (PMC). Physicians and researchers can find your work through PubMed , helping you reach the widest possible audience. The journal is also indexed in the Web of Science Core Collection . Oxford Medical Case Reports publishes case reports under the following categories: Allergy Audiovestibular medicine Cardiology and cardiovascular systems Critical care medicine Dermatology Emergency medicine Endocrinology and metabolism Gastroenterology and hepatology Geriatrics and gerontology Haematology Immunology Infectious diseases and tropical medicine Medical disorders in pregnancy Medical ophthalmology Nephrology Neurology Oncology Paediatrics Pain Palliative medicine Pharmacology and pharmacy Psychiatry Radiology, nuclear medicine, and medical imaging Respiratory disorders Rheumatology Sexual and reproductive health Sports Medicine Substance abuse.
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