{"title":"Collective transport of particles and cells enabled by wavelength-division multiplexing in microcavity cascade optical tweezers.","authors":"Jianguo Jiang, Qizan Shi, Weida Chen, Xu Liu, Linzhi Yao, Zhaoqi Ji, Minghui Zhang, Xiufang Wang, Peng Chen, Taiji Dong, Chunlei Jiang","doi":"10.1364/OL.553192","DOIUrl":null,"url":null,"abstract":"<p><p>This study presents a microcavity cascade optical tweezer (MCOT) system incorporating wavelength-division multiplexing for collective transport of particles and cells in biomedical applications. The MCOT system traps and transports yeast cells (5 μm) and silica microspheres using 980 nm and 1550 nm lasers, with a maximum capacity of six particles. Under 980 nm laser illumination, capillary microflow force surpasses optical forces, stably trapping particles and cells in the microcavity. At 1550 nm, significant heat absorption excites thermophoretic forces, which, combined with optical forces, enhance particle transport. Experimental results closely match simulations, confirming the system's potential for efficient particle and cell transport, especially for drug and cell delivery applications.</p>","PeriodicalId":19540,"journal":{"name":"Optics letters","volume":"50 7","pages":"2167-2170"},"PeriodicalIF":3.1000,"publicationDate":"2025-04-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":"0","resultStr":null,"platform":"Semanticscholar","paperid":null,"PeriodicalName":"Optics letters","FirstCategoryId":"101","ListUrlMain":"https://doi.org/10.1364/OL.553192","RegionNum":2,"RegionCategory":"物理与天体物理","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":null,"EPubDate":"","PubModel":"","JCR":"Q2","JCRName":"OPTICS","Score":null,"Total":0}
引用次数: 0
Abstract
This study presents a microcavity cascade optical tweezer (MCOT) system incorporating wavelength-division multiplexing for collective transport of particles and cells in biomedical applications. The MCOT system traps and transports yeast cells (5 μm) and silica microspheres using 980 nm and 1550 nm lasers, with a maximum capacity of six particles. Under 980 nm laser illumination, capillary microflow force surpasses optical forces, stably trapping particles and cells in the microcavity. At 1550 nm, significant heat absorption excites thermophoretic forces, which, combined with optical forces, enhance particle transport. Experimental results closely match simulations, confirming the system's potential for efficient particle and cell transport, especially for drug and cell delivery applications.
期刊介绍：
The Optical Society (OSA) publishes high-quality, peer-reviewed articles in its portfolio of journals, which serve the full breadth of the optics and photonics community.
Optics Letters offers rapid dissemination of new results in all areas of optics with short, original, peer-reviewed communications. Optics Letters covers the latest research in optical science, including optical measurements, optical components and devices, atmospheric optics, biomedical optics, Fourier optics, integrated optics, optical processing, optoelectronics, lasers, nonlinear optics, optical storage and holography, optical coherence, polarization, quantum electronics, ultrafast optical phenomena, photonic crystals, and fiber optics. Criteria used in determining acceptability of contributions include newsworthiness to a substantial part of the optics community and the effect of rapid publication on the research of others. This journal, published twice each month, is where readers look for the latest discoveries in optics.
求助内容：
应助结果提醒方式：
京公网安备 11010802042870号
