Urogenital Schistosomiasis Mimicking IgG4-RD in a Patient With HIV.

IF 3.8 4区医学 Q2 IMMUNOLOGY

Open Forum Infectious Diseases Pub Date : 2025-03-18 eCollection Date: 2025-04-01 DOI:10.1093/ofid/ofaf136

Guillemette Gagey, Didier Sorial, Camille Rasmussen, Frédéric Mechai, Lionel Galicier, Jérôme Vérine, Eric Oksenhendler, Rémi Bertinchamp, Elsa Poullot, David Boutboul

引用次数: 0

Abstract

This article reports a case of urogenital schistosomiasis mimicking IgG4-related disease (IgG4-RD) in a 47-year-old immunocompromised man with HIV. Initially diagnosed with IgG4-RD, further biopsies revealed schistosoma eggs. Elevated IgG4 levels indicated a Th2 immune response, highlighting its complex role in antischistosomal immunity and the need for careful differential diagnosis.

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HIV患者中模拟IgG4-RD的泌尿生殖道血吸虫病

本文报告一例模拟igg4相关疾病（IgG4-RD）的泌尿生殖道血吸虫病在47岁的免疫功能低下的艾滋病毒感染者。最初诊断为IgG4-RD，进一步活检显示为血吸虫卵。IgG4水平升高表明Th2免疫应答，强调其在抗血吸虫免疫中的复杂作用，需要仔细鉴别诊断。

本文章由计算机程序翻译，如有差异，请以英文原文为准。

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来源期刊

Open Forum Infectious Diseases Medicine-Neurology (clinical)

CiteScore

6.70

自引率

4.80%

发文量

630

审稿时长

9 weeks

期刊介绍： Open Forum Infectious Diseases provides a global forum for the publication of clinical, translational, and basic research findings in a fully open access, online journal environment. The journal reflects the broad diversity of the field of infectious diseases, and focuses on the intersection of biomedical science and clinical practice, with a particular emphasis on knowledge that holds the potential to improve patient care in populations around the world. Fully peer-reviewed, OFID supports the international community of infectious diseases experts by providing a venue for articles that further the understanding of all aspects of infectious diseases.