Paracoccidioidomycosis as a Manifestation of Immune Reconstitution Inflammatory Syndrome in an HIV Patient: An Uncommon Presentation.

IF 3.8 4区医学 Q2 IMMUNOLOGY

Open Forum Infectious Diseases Pub Date : 2025-03-08 eCollection Date: 2025-04-01 DOI:10.1093/ofid/ofaf141

Amanda P O Silva, Francine C Lóta, Marilene M Paschoal, Ana H P C Carneiro, Luiz A A Lima, Isabel C M Mendes, Sergio A L Souza, Maria Célia Djahjah

引用次数: 0

Abstract

A 50-year-old HIV-positive woman, nonadherent to antiretroviral therapy, developed asthenia, weight loss, and lymphadenopathy after restarting treatment. Imaging revealed adenopathies and a breast nodule, with biopsies confirming Paracoccidioides brasiliensis. Despite initial therapy failure (trimethoprim-sulfamethoxazole), liposomal amphotericin, corticosteroids, and a regimen change led to partial improvement until a psoas abscess required drainage, ultimately stabilizing her condition.

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来源期刊

Open Forum Infectious Diseases Medicine-Neurology (clinical)

CiteScore

6.70

自引率

4.80%

发文量

630

审稿时长

9 weeks

期刊介绍： Open Forum Infectious Diseases provides a global forum for the publication of clinical, translational, and basic research findings in a fully open access, online journal environment. The journal reflects the broad diversity of the field of infectious diseases, and focuses on the intersection of biomedical science and clinical practice, with a particular emphasis on knowledge that holds the potential to improve patient care in populations around the world. Fully peer-reviewed, OFID supports the international community of infectious diseases experts by providing a venue for articles that further the understanding of all aspects of infectious diseases.