Comparative efficacy of common rehabilitation treatments for patients with neuropathic pain after spinal cord injury: a systematic review and network meta-analysis.
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引用次数: 0
Abstract
Background: Neuropathic pain is a prevalent complication following spinal cord injury, imposing severe physical and psychological burdens on affected individuals. It often hinders complete physical and mental recovery. Despite numerous rehabilitation interventions being explored and implemented, the optimal treatment strategy for neuropathic pain post-spinal cord injury remains a subject of ongoing debate. To address this uncertainty, a comprehensive network meta-analysis is imperative. This analysis aims to compare the effectiveness of various rehabilitation interventions and guide clinical staff in selecting the most efficacious treatment to alleviate patients' physical and psychological distress.
Methods: Embase, PubMed, Scopus, Web of Science, CNKI, Wan Fang, Vip Journal Integration Platform and Sinomed were searched from the establishment of the database to 13 June 2024. Employing ROB 2.0 and Stata 18.0 for literature selection, quality evaluation and meta-analysis, the effectiveness of various rehabilitation interventions was assessed. These interventions were evaluated using network-level and cumulative level surface under the cumulative ranking area analysis.
Results: The review included 31 studies involving 1820 patients. According to the cumulative ranking area ranking of 17 therapies, the best three interventions for reducing pain are repetitive transcranial magnetic stimulation, acupuncture, and intermittent theta burst stimulation.
Conclusions: The intermittent theta burst stimulation treatment demonstrated superior efficacy in managing pain after spinal cord injury, closely followed by acupuncture and repetitive transcranial magnetic stimulation. This analysis provides a solid foundation for clinical staff to select the appropriate therapeutic approaches.
背景：神经性疼痛是脊髓损伤后常见的并发症，给患者带来严重的生理和心理负担。它经常阻碍身体和精神的完全恢复。尽管许多康复干预措施正在探索和实施，脊髓损伤后神经性疼痛的最佳治疗策略仍然是一个持续争论的主题。为了解决这种不确定性，全面的网络元分析势在必行。本分析旨在比较各种康复干预措施的效果，指导临床工作人员选择最有效的治疗方法，减轻患者的身心困扰。方法：检索自建库至2024年6月13日，检索Embase、PubMed、Scopus、Web of Science、CNKI、万方、Vip期刊集成平台、Sinomed。采用ROB 2.0和Stata 18.0进行文献选择、质量评价和meta分析，评估各种康复干预措施的有效性。在累积排序面积分析下，采用网络水平和累积水平面对这些干预措施进行评价。结果：纳入31项研究，涉及1820例患者。根据17种治疗方法的累积排名区域排名，重复性经颅磁刺激、针刺和间歇性θ波爆发刺激是缓解疼痛效果最好的3种干预措施。结论：间歇性θ波脉冲刺激治疗对脊髓损伤后疼痛的治疗效果较好，针刺和反复经颅磁刺激紧随其后。该分析为临床工作人员选择合适的治疗方法提供了坚实的基础。
期刊介绍：
Neurological Sciences is intended to provide a medium for the communication of results and ideas in the field of neuroscience. The journal welcomes contributions in both the basic and clinical aspects of the neurosciences. The official language of the journal is English. Reports are published in the form of original articles, short communications, editorials, reviews and letters to the editor. Original articles present the results of experimental or clinical studies in the neurosciences, while short communications are succinct reports permitting the rapid publication of novel results. Original contributions may be submitted for the special sections History of Neurology, Health Care and Neurological Digressions - a forum for cultural topics related to the neurosciences. The journal also publishes correspondence book reviews, meeting reports and announcements.
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