Current Problems of Pharmaceutical Compounding in Hungary.

Abstract

On average, at least about 85-90% of compounded (magistral) medicinal products are prescribed by doctors in Hungary on an individual basis, outside the official National Formulary of compounded medicinal products (Formulae Normales or FoNo). Until now, the problem has been that no one has had a comprehensive understanding of the domestic non-FoNo compounded medicinal products, so the authorities have not been able to issue detailed regulations to address typical problems. However, from the database www.magisztralisvenyek.hu, available since 2020, the characteristics and typical errors of compounding can be well studied. In the absence of reforms, the field of compounded medicinal products in Hungary has become very outdated compared to some developed countries (especially Germany) and has entered a crisis. Doctors are prescribing a lot of compounded products of unproven efficacy, safety and stability. The Author gives an overview of the characteristics and problems of some groups of non-FoNo compounded preparations, describes the historical reasons for the current situation and proposes a reform of compounding.