Acute Esophageal Necrosis (Gurvits Syndrome): A Rare Cause of Upper Gastrointestinal Bleeding in Somalia.

IF 0.7 Q3 MEDICINE, GENERAL & INTERNAL
International Medical Case Reports Journal Pub Date : 2025-03-26 eCollection Date: 2025-01-01 DOI:10.2147/IMCRJ.S509079
Esmail Husein Mohamud, Ali Ahmed Nor, Liban Hussein Ahmed, Ahmed Saed Hussein, Mohamed Ali Ahmed
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Abstract

Acute esophageal necrosis, also known as Gurvits syndrome, is a rare condition due to ischemic compromise and thromboembolic injury to esophagus associated with high mortality. Endoscopically, it is characterized by the circumferential black discoloration of the esophagus. We present the case of a 55-year-old male with a history of multiple comorbidities, including uncontrolled type 2 diabetes mellitus, hypertension, smoker, peripheral arterial disease, and a right above-ankle amputation, who presented with active hematemesis and melena with hemodynamic instability. An esophagogastroduodenoscopy revealed diffuse, circumferential necrotizing esophagitis with black discoloration and ulcerations affecting the middle and distal thirds of the esophagus. The severity increased from the proximal to the distal esophagus, abruptly ending at the gastroesophageal junction. These endoscopic findings, combined with the patient's medical history, were consistent with a diagnosis of acute esophageal necrosis. The patient was admitted to the ward and managed conservatively with intravenous fluid resuscitation, IV proton pump inhibitor twice daily, sucralfate 1 gram every six hours, strict glycemic control using insulin, total parenteral nutrition, empirical IV antibiotics, and placed on nil-per-oral (NPO) for three days. A follow-up esophagogastroduodenoscopy conducted twenty-two days post-admission showed complete healing of the esophageal mucosa without stricture formation. Despite its rarity, prompt diagnosis and management of acute esophageal necrosis are crucial due to its association with high morbidity and mortality, as well as the need to minimize complications such as perforations and strictures, particularly in patients with comorbidities. This case report aims to raise awareness among clinicians in Somalia of this condition as a differential diagnosis in upper gastrointestinal bleeding and to highlight the importance of timely intervention to prevent adverse outcomes.

急性食管坏死(Gurvits综合征):索马里上消化道出血的罕见原因。
急性食管坏死,也称为Gurvits综合征,是一种罕见的疾病,由于缺血妥协和血栓栓塞性食管损伤相关的高死亡率。内窥镜下,其特征是食道周围呈黑色变色。我们报告一例55岁男性,有多种合并症史,包括未控制的2型糖尿病、高血压、吸烟者、外周动脉疾病和右脚踝以上截肢,表现为活动性呕血和黑黑伴血流动力学不稳定。食管胃十二指肠镜检查显示弥漫性,周状坏死性食管炎,伴黑色变色和溃疡,影响食管中部和远端三分之一。从食管近端到远端加重,直至胃食管交界处终止。这些内窥镜检查结果,结合患者的病史,符合急性食管坏死的诊断。患者入院后给予静脉液体复苏、每日2次静脉注射质子泵抑制剂、每6小时1克硫硫钠、胰岛素严格控制血糖、全肠外营养、经经验静脉注射抗生素,并给予口服无药(NPO)治疗3天。入院后22天进行的食管胃十二指肠镜检查显示食管黏膜完全愈合,无狭窄形成。尽管罕见,但急性食管坏死的及时诊断和治疗至关重要,因为它与高发病率和死亡率有关,而且需要尽量减少穿孔和狭窄等并发症,特别是在有合并症的患者中。本病例报告旨在提高索马里临床医生对这种情况的认识,将其作为上消化道出血的鉴别诊断,并强调及时干预以预防不良后果的重要性。
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来源期刊
International Medical Case Reports Journal
International Medical Case Reports Journal MEDICINE, GENERAL & INTERNAL-
CiteScore
1.40
自引率
0.00%
发文量
135
审稿时长
16 weeks
期刊介绍: International Medical Case Reports Journal is an international, peer-reviewed, open access, online journal publishing original case reports from all medical specialties. Submissions should not normally exceed 3,000 words or 4 published pages including figures, diagrams and references. As of 1st April 2019, the International Medical Case Reports Journal will no longer consider meta-analyses for publication.
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