Abdulrahman Bakather, Hind Amin, Waleed Nasif, Samir Shoughy
{"title":"Adverse effects of topical tacrolimus compounded ophthalmic preparations.","authors":"Abdulrahman Bakather, Hind Amin, Waleed Nasif, Samir Shoughy","doi":"10.1080/15569527.2025.2485139","DOIUrl":null,"url":null,"abstract":"<p><strong>Purpose: </strong>The main aim of this review is to provide an overview of the key ocular side effects associated with topical tacrolimus compounded ophthalmic preparations Materials and methods: Review of literature using Pubmed database.</p><p><strong>Results: </strong>The use of topical tacrolimus may be associated with side effects ranging from mild ocular discomfort to more server complications like loss of integrity of corneal surface, corneal ulcer and infectious keratitis. However, the use of topical tacrolimus is not associated with increased incidence of secondary glaucoma or cataract.</p><p><strong>Conclusion: </strong>It is imperative to understand the potential side effects associated with topical tacrolimus ophthalmic preparations to optimize the treatment outcomes and guarantee patient safety. Routine ophthalmic examinations should be conducted to detect these side effects early and address them appropriately.</p>","PeriodicalId":11023,"journal":{"name":"Cutaneous and Ocular Toxicology","volume":" ","pages":"1-5"},"PeriodicalIF":1.6000,"publicationDate":"2025-04-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":"0","resultStr":null,"platform":"Semanticscholar","paperid":null,"PeriodicalName":"Cutaneous and Ocular Toxicology","FirstCategoryId":"3","ListUrlMain":"https://doi.org/10.1080/15569527.2025.2485139","RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":null,"EPubDate":"","PubModel":"","JCR":"Q3","JCRName":"OPHTHALMOLOGY","Score":null,"Total":0}
引用次数: 0
Abstract
Purpose: The main aim of this review is to provide an overview of the key ocular side effects associated with topical tacrolimus compounded ophthalmic preparations Materials and methods: Review of literature using Pubmed database.
Results: The use of topical tacrolimus may be associated with side effects ranging from mild ocular discomfort to more server complications like loss of integrity of corneal surface, corneal ulcer and infectious keratitis. However, the use of topical tacrolimus is not associated with increased incidence of secondary glaucoma or cataract.
Conclusion: It is imperative to understand the potential side effects associated with topical tacrolimus ophthalmic preparations to optimize the treatment outcomes and guarantee patient safety. Routine ophthalmic examinations should be conducted to detect these side effects early and address them appropriately.
期刊介绍：
Cutaneous and Ocular Toxicology is an international, peer-reviewed journal that covers all types of harm to cutaneous and ocular systems. Areas of particular interest include pharmaceutical and medical products; consumer, personal care, and household products; and issues in environmental and occupational exposures.
In addition to original research papers, reviews and short communications are invited, as well as concise, relevant, and critical reviews of topics of contemporary significance.
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