Effect of hypochlorous acid in open wound healing.

IF 1.9
Bioinformation Pub Date : 2024-11-30 eCollection Date: 2024-01-01 DOI:10.6026/9732063002001619
Spurgeon Raj Jalem, Purimitla Usharani
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Abstract

Wound healing is a complex process involving multiple stages to restore the integrity and function of damaged tissues. Researchers are exploring the therapeutic potential of HOCl in treating infections and inflammatory conditions, given its efficacy in killing pathogens and modulating immune responses. The present study is a prospective study aimed to know the wound healing nature of HOCl on open wounds in patients attending out-patient department. The study was conducted for a period of one year Jan 2023 to Jan 2024 at Bliss Hospital, Hyderabad, Telangana district, India. Hypochlorous acid (Vida solutions, Pvt. Ltd) was used to irrigate the open wound. Among the 10 reported cases, three were females and seven were males. Most of the cases were reported from middle-age and old-age persons except one paediatric case of age 3 years a female girl. A male patient of age 72 years with co-morbidities diabetes and hypertension suffering with chronic wound on left leg for a period of 35 years because of thorn prick injury. The complete wound healing took nearly 15 weeks in this patient. The wound healing takes place 8 to 15 weeks maximum in all the 10 cases and the above findings concluded that, these features lead to a stabilized HOCl solution as an ideal wound care agent.

次氯酸对开放性伤口愈合的影响。
伤口愈合是一个复杂的过程,涉及多个阶段,以恢复受损组织的完整性和功能。研究人员正在探索HOCl在治疗感染和炎症方面的治疗潜力,因为它具有杀死病原体和调节免疫反应的功效。本研究是一项前瞻性研究,旨在了解HOCl对门诊患者开放性伤口的愈合性质。该研究于2023年1月至2024年1月在印度特伦甘纳地区海得拉巴的布利斯医院进行,为期一年。使用次氯酸(Vida solutions, Pvt. Ltd .)冲洗开放性创面。在10宗呈报个案中,3名女性及7名男性。除1例3岁儿童女童外,大多数病例报告为中老年人。男性患者,72岁,合并糖尿病和高血压,左腿因刺扎伤慢性创面35年。该患者伤口完全愈合用时近15周。在所有10例病例中,伤口愈合时间最长为8至15周,上述结果表明,这些特征导致稳定的HOCl溶液作为理想的伤口护理剂。
本文章由计算机程序翻译,如有差异,请以英文原文为准。
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来源期刊
Bioinformation
Bioinformation MATHEMATICAL & COMPUTATIONAL BIOLOGY-
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