A study on the effect of fibromyalgia severity on sleep quality using inflammatory markers.

IF 1.9
Bioinformation Pub Date : 2024-11-30 eCollection Date: 2024-01-01 DOI:10.6026/9732063002001608
Ruchi Singh, Jyotsana Rai, Akash Pathak, Nirendra Kumar Rai
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引用次数: 0

Abstract

Fibromyalgia syndrome (FMS) is a widespread musculoskeletal pain, often accompanied by fatigue and sleep disturbances. Poor sleep exacerbates inflammation and pain, potentially increasing levels of inflammatory markers. This study explored the effect of FMS severity on CRP levels, sleep quality and pain intensity. 89 FMS individuals were explored for FMS severity, pain and sleep quality. CRP levels in blood and erythrocyte sedimentation rate (ESR) were measured to assess inflammation. An increase in FMS severity was associated with an increase in CRP and ESR levels, pain intensity and sleep disturbances. However, a positive correlation between CRP levels and sleep quality indicates that Poor sleep quality in FMS may contribute to elevated CRP levels. Addressing sleep quality may mitigate the severity of FMS and its associated symptoms.

利用炎症标志物研究纤维肌痛严重程度对睡眠质量的影响。
纤维肌痛综合征(FMS)是一种广泛的肌肉骨骼疼痛,通常伴有疲劳和睡眠障碍。睡眠不足会加剧炎症和疼痛,可能会增加炎症标志物的水平。本研究探讨了FMS严重程度对CRP水平、睡眠质量和疼痛强度的影响。对89名FMS患者进行了FMS严重程度、疼痛和睡眠质量的调查。测量血液中CRP水平和红细胞沉降率(ESR)来评估炎症。FMS严重程度的增加与CRP和ESR水平、疼痛强度和睡眠障碍的增加有关。然而,CRP水平与睡眠质量正相关表明FMS睡眠质量差可能导致CRP水平升高。解决睡眠质量问题可以减轻FMS及其相关症状的严重程度。
本文章由计算机程序翻译,如有差异,请以英文原文为准。
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来源期刊
Bioinformation
Bioinformation MATHEMATICAL & COMPUTATIONAL BIOLOGY-
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