Audiological findings in patients with leprosy.

IF 1.2 4区 医学 Q3 OTORHINOLARYNGOLOGY
Mahmut Uzut, Senem Erdur Uzut, Fatma Tülin Kayhan, Levent Küfeciler, Zübeyde Elmalı
{"title":"Audiological findings in patients with leprosy.","authors":"Mahmut Uzut, Senem Erdur Uzut, Fatma Tülin Kayhan, Levent Küfeciler, Zübeyde Elmalı","doi":"10.1080/00016489.2025.2482170","DOIUrl":null,"url":null,"abstract":"<p><strong>Background: </strong>Leprosy, caused by <i>Mycobacterium leprae</i>, is a chronic infectious disease primarily affecting the skin and nervous system. The vestibulocochlear nerve may also be impacted, potentially leading to auditory dysfunction.</p><p><strong>Aims/objectives: </strong>This study investigates the effects of leprosy on the vestibulocochlear nerve and its impact on auditory function through a comprehensive audiological evaluation.</p><p><strong>Material and methods: </strong>A total of 15 leprosy patients and 15 healthy individuals were included. Audiological assessments were conducted at a tertiary care hospital. All participants underwent pure-tone audiometry, speech audiometry, tympanometry, acoustic reflex testing, otoacoustic emissions (OAE), and brainstem auditory evoked response (BERA) tests. Hearing thresholds, wave latencies, and neural conduction were analyzed.</p><p><strong>Results: </strong>Hearing thresholds were significantly higher in leprosy patients than in the control group. BERA results showed a significant prolongation of wave I and wave III latencies in leprosy patients, indicating dysfunction at the level of the acoustic nerve and superior olivary complex.</p><p><strong>Conclusions and significance: </strong>Leprosy may contribute to auditory dysfunction by affecting the myelin sheath of the peripheral and central nervous systems. These findings provide insight into the impact of leprosy on the vestibulocochlear nerve and emphasize the importance of audiological evaluation in leprosy patients.</p>","PeriodicalId":6880,"journal":{"name":"Acta Oto-Laryngologica","volume":" ","pages":"1-5"},"PeriodicalIF":1.2000,"publicationDate":"2025-03-31","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":"0","resultStr":null,"platform":"Semanticscholar","paperid":null,"PeriodicalName":"Acta Oto-Laryngologica","FirstCategoryId":"3","ListUrlMain":"https://doi.org/10.1080/00016489.2025.2482170","RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":null,"EPubDate":"","PubModel":"","JCR":"Q3","JCRName":"OTORHINOLARYNGOLOGY","Score":null,"Total":0}
引用次数: 0

Abstract

Background: Leprosy, caused by Mycobacterium leprae, is a chronic infectious disease primarily affecting the skin and nervous system. The vestibulocochlear nerve may also be impacted, potentially leading to auditory dysfunction.

Aims/objectives: This study investigates the effects of leprosy on the vestibulocochlear nerve and its impact on auditory function through a comprehensive audiological evaluation.

Material and methods: A total of 15 leprosy patients and 15 healthy individuals were included. Audiological assessments were conducted at a tertiary care hospital. All participants underwent pure-tone audiometry, speech audiometry, tympanometry, acoustic reflex testing, otoacoustic emissions (OAE), and brainstem auditory evoked response (BERA) tests. Hearing thresholds, wave latencies, and neural conduction were analyzed.

Results: Hearing thresholds were significantly higher in leprosy patients than in the control group. BERA results showed a significant prolongation of wave I and wave III latencies in leprosy patients, indicating dysfunction at the level of the acoustic nerve and superior olivary complex.

Conclusions and significance: Leprosy may contribute to auditory dysfunction by affecting the myelin sheath of the peripheral and central nervous systems. These findings provide insight into the impact of leprosy on the vestibulocochlear nerve and emphasize the importance of audiological evaluation in leprosy patients.

求助全文
约1分钟内获得全文 求助全文
来源期刊
Acta Oto-Laryngologica
Acta Oto-Laryngologica 医学-耳鼻喉科学
CiteScore
2.50
自引率
0.00%
发文量
99
审稿时长
3-6 weeks
期刊介绍: Acta Oto-Laryngologica is a truly international journal for translational otolaryngology and head- and neck surgery. The journal presents cutting-edge papers on clinical practice, clinical research and basic sciences. Acta also bridges the gap between clinical and basic research.
×
引用
GB/T 7714-2015
复制
MLA
复制
APA
复制
导出至
BibTeX EndNote RefMan NoteFirst NoteExpress
×
提示
您的信息不完整,为了账户安全,请先补充。
现在去补充
×
提示
您因"违规操作"
具体请查看互助需知
我知道了
×
提示
确定
请完成安全验证×
copy
已复制链接
快去分享给好友吧!
我知道了
右上角分享
点击右上角分享
0
联系我们:info@booksci.cn Book学术提供免费学术资源搜索服务,方便国内外学者检索中英文文献。致力于提供最便捷和优质的服务体验。 Copyright © 2023 布克学术 All rights reserved.
京ICP备2023020795号-1
ghs 京公网安备 11010802042870号
Book学术文献互助
Book学术文献互助群
群 号:481959085
Book学术官方微信