Familial Frontal Fibrosing Alopecia Occurs Early in Daughters With Affected Mothers: A Case Report and a Review of the Literature.

Abstract

Frontal fibrosing alopecia (FFA) is a form of cicatricial alopecia that is being increasingly diagnosed in recent years. It predominantly affects post-menopausal women of various ethnic backgrounds, but cases have also been reported in pre-menopausal women and rarely in men. Eleven familial cases of FFA have been published in the literature, with some authors raising speculation about potential genetic predisposition or shared exposure to environmental factors as triggers for the condition. Despite this, there remains a lack of detailed characterisation of the clinical features specific to familial cases of FFA. In this report, we aim to contribute to the understanding of FFA by presenting the first Australian case of familial FFA involving a mother and her daughter, while also attempting to define the clinical distinguishing features in familial FFA and sporadic FFA.