Synthesis of 3,4-unsubstituted isoquinolone derivatives from benzimidates and vinylene carbonate via cobalt(iii)-catalyzed C–H activation/cyclization†

IF 2.9 3区化学 Q1 CHEMISTRY, ORGANIC

Organic & Biomolecular Chemistry Pub Date : 2025-03-20 DOI:10.1039/D5OB00319A

Weiyan Xu, Haowen Dang, Huiru Sheng, Jiabin Shen and Min Wang

引用次数: 0

Abstract

A cobalt(III)-catalyzed C–H activation/cyclization of benzimidates and vinylene carbonate has been developed. Various benzimidates showed good compatibility, providing isoquinolone derivatives in moderate to good yields. This strategy employs the inexpensive Co(III) as the catalyst and provides an efficient and practical solution for the synthesis of medicinally valuable 3,4-unsubstituted isoquinolone derivatives.

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来源期刊

Organic & Biomolecular Chemistry 化学-有机化学

CiteScore

5.50

自引率

9.40%

发文量

1056

审稿时长

1.3 months

期刊介绍： Organic & Biomolecular Chemistry is an international journal using integrated research in chemistry-organic chemistry. Founded in 2003 by the Royal Society of Chemistry, the journal is published in Semimonthly issues and has been indexed by SCIE, a leading international database. The journal focuses on the key research and cutting-edge progress in the field of chemistry-organic chemistry, publishes and reports the research results in this field in a timely manner, and is committed to becoming a window and platform for rapid academic exchanges among peers in this field. The journal's impact factor in 2023 is 2.9, and its CiteScore is 5.5.