NHC-catalysed synthesis of hydroxy methylene-bridged formyl-di-xylofuranose: access to tetrakis and spiro tricyclic xylofuranose.

IF 2.9 3区化学 Q1 CHEMISTRY, ORGANIC

Organic & Biomolecular Chemistry Pub Date : 2025-03-31 DOI:10.1039/d5ob00259a

Norein Sakander, Rahul Haldar, Debaraj Mukherjee

引用次数: 0

Abstract

Herein, the role of N-heterocyclic carbenes (NHC) as a Brønsted base in the transformation of xylofuranose aldehyde has been explored. Furanose aldehyde undergoes intermolecular self-condensation catalyzed by thiazolium-derived carbene, producing hydroxy methylene-bridged formyl-di-xylofuranose retaining the C-4 aldehyde. Furthermore, modification of the hydroxy methylene-linked disaccharide yields spiro[furano-4,5-pyrano[3,2-b]furanose] and oxy-methylene-bridged di-formyl-xylofuranose cyclic tetrasaccharide.

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来源期刊

Organic & Biomolecular Chemistry 化学-有机化学

CiteScore

5.50

自引率

9.40%

发文量

1056

审稿时长

1.3 months

期刊介绍： Organic & Biomolecular Chemistry is an international journal using integrated research in chemistry-organic chemistry. Founded in 2003 by the Royal Society of Chemistry, the journal is published in Semimonthly issues and has been indexed by SCIE, a leading international database. The journal focuses on the key research and cutting-edge progress in the field of chemistry-organic chemistry, publishes and reports the research results in this field in a timely manner, and is committed to becoming a window and platform for rapid academic exchanges among peers in this field. The journal's impact factor in 2023 is 2.9, and its CiteScore is 5.5.