{"title":"Metabolic encephalopathy associated with uraemic syndrome and hyperammonaemia in a horse presenting with renal failure","authors":"T. Fernandes, M. Robin","doi":"10.1111/eve.14096","DOIUrl":null,"url":null,"abstract":"<div>\n \n <p>A 3-year-old racing Arabian mare was admitted to the hospital with a 5-day history of muscle pain, lethargy and anorexia. The mare arrived at the hospital with marked neurological abnormalities, dehydration and melaena. Investigation revealed severe azotaemia, acute renal failure, hyperammonaemia and evidence of recent myopathy. Therapeutic objectives were the correction of fluid deficiencies and restoration of normal renal function and urine production. The mare responded rapidly to treatment and was discharged after 12 days, before going on to race the following year. To the authors' knowledge, this is the first report of survival of a case of acute renal failure with metabolic encephalopathy associated with hyperammonaemia and uraemic syndrome in the horse. Additionally, the case had symptoms of GI disease consistent with uraemic damage to the intestine.</p>\n </div>","PeriodicalId":11786,"journal":{"name":"Equine Veterinary Education","volume":"37 5","pages":"e85-e91"},"PeriodicalIF":0.8000,"publicationDate":"2025-01-10","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":"0","resultStr":null,"platform":"Semanticscholar","paperid":null,"PeriodicalName":"Equine Veterinary Education","FirstCategoryId":"97","ListUrlMain":"https://onlinelibrary.wiley.com/doi/10.1111/eve.14096","RegionNum":4,"RegionCategory":"农林科学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":null,"EPubDate":"","PubModel":"","JCR":"Q3","JCRName":"VETERINARY SCIENCES","Score":null,"Total":0}
引用次数: 0
Abstract
A 3-year-old racing Arabian mare was admitted to the hospital with a 5-day history of muscle pain, lethargy and anorexia. The mare arrived at the hospital with marked neurological abnormalities, dehydration and melaena. Investigation revealed severe azotaemia, acute renal failure, hyperammonaemia and evidence of recent myopathy. Therapeutic objectives were the correction of fluid deficiencies and restoration of normal renal function and urine production. The mare responded rapidly to treatment and was discharged after 12 days, before going on to race the following year. To the authors' knowledge, this is the first report of survival of a case of acute renal failure with metabolic encephalopathy associated with hyperammonaemia and uraemic syndrome in the horse. Additionally, the case had symptoms of GI disease consistent with uraemic damage to the intestine.
期刊介绍：
Equine Veterinary Education (EVE) is the official journal of post-graduate education of both the British Equine Veterinary Association (BEVA) and the American Association of Equine Practitioners (AAEP).
Equine Veterinary Education is a monthly, peer-reviewed, subscription-based journal, integrating clinical research papers, review articles and case reports from international sources, covering all aspects of medicine and surgery relating to equids. These papers facilitate the dissemination and implementation of new ideas and techniques relating to clinical veterinary practice, with the ultimate aim of promoting best practice. New developments are placed in perspective, encompassing new concepts and peer commentary. The target audience is veterinarians primarily engaged in the practise of equine medicine and surgery. The educational value of a submitted article is one of the most important criteria that are assessed when deciding whether to accept it for publication. Articles do not necessarily need to contain original or novel information but we welcome submission of this material. The educational value of an article may relate to articles published with it (e.g. a Case Report may not have direct educational value but an associated Clinical Commentary or Review Article published alongside it will enhance the educational value).
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