Dermatofitosis causadas por Nannizzia gypsea: informe de 155 casos en el oeste de México

Abstract

Background

Dermatophytosis caused by Nannizzia gypsea are considered rare. The clinical picture is indistinguishable from that produced by other dermatophytes, but, being this a geophilic fungus, it can cause more inflammatory disease.

Methods

Retrospective study. Patients with positive culture for N. gypsea observed at the Dermatological Institute of Jalisco «Dr. José Barba Rubio», from 2001 to 2023, were included. Frequency, sex, age, evolution, and clinical variant were investigated. We compared the findings between the pediatric versus adult population. Descriptive and inferential statistics were used.

Results

Over 23 years, 155 patients were diagnosed (6.7 cases per year). Female sex predominated (53.5%). The median age was 9 years (minimum 1 year and maximum 85 years), the more affected age group was 1 to 10 years (54.2%). The median time of evolution was 30 days (minimum one day and maximum 3 years), and 74.8% had an evolution ≤ 30 days. Tinea capitis predominated in pediatric patients (41.0%, P < .01) whereas tinea corporis predominated in adults (72.7%, P < .01). Inflammatory tinea was more prevalent in the pediatric population (21.0% vs. 3.6%, P < .01).

Conclusion

The ability of N. gypsea to cause inflammatory tinea was observed primarily in pediatric patients. Since there is no clinical data to suspect this fungus, it will always be necessary to carry out a mycological study to identify the species and to implement the appropriate treatment.