Evaluation of Zhuhai DL Biotech's BT24 automated blood culture system

IF 2.6 4区医学 Q3 INFECTIOUS DISEASES

Enfermedades infecciosas y microbiologia clinica Pub Date : 2025-04-01 DOI:10.1016/j.eimc.2024.07.003

Blanca Carrasco, Elena Hidalgo, Gloria Zaragoza, Juan-Ignacio Alós

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引用次数: 0

Abstract

Introduction

For the microbiological diagnosis of bacteremia and fungemia, it is essential to use automated blood culture systems that guarantee good performance in the detection of microorganisms.

We evaluated the BT24 system for blood cultures (BCs) by comparing it with the BACTEC™ FX system in detection of positive spiked BCs and bottles, subsequent growth of the microorganism, and time to detection (TTD).

Methods

The parallel analysis of both systems was performed with 160 strains of 31 different species, each inoculated under the same conditions and simultaneously in six BC bottles.

The Chi-square test was used for comparison per BC and per bottle detection. Wilcoxon test and Student's t-test were used for comparison of TTDs.

Results

Overall, the following BC (aerobic bottle + anaerobic bottle) were detected as positive: 160/160 (100%) in BACTEC FX and 158/160 (98.7%) in BT24 (p = 0.31). Furthermore, the following pediatric BCs (1 single bottle, aerobic) were also detected: 159/160 (99.4%) in BACTEC FX and 156/160 (97.5%) in BT24 (p = 0.17).

TTDs were longer with BT24 system than with BACTEC FX system, especially for Staphylococcus aureus strains.

Conclusions

We consider the BT24 system with good performance and specificity comparable to the reference system, but inferior in TTD.

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来源期刊

Enfermedades infecciosas y microbiologia clinica 医学-传染病学

CiteScore

2.10

自引率

8.00%

发文量

194

审稿时长

29 days

期刊介绍： Hoy está universalmente reconocida la renovada y creciente importancia de la patología infecciosa: aparición de nuevos agentes patógenos, de cepas resistentes, de procesos con expresión clínica hasta ahora desconocida, de cuadros de una gran complejidad. Paralelamente, la Microbiología y la Infectología Clínicas han experimentado un gran desarrollo como respuesta al reto planteado por la actual patología infecciosa. Enfermedades Infecciosas y Microbiología Clínica es la Publicación Oficial de la Sociedad Española SEIMC. Cumple con la garantía científica de esta Sociedad, la doble función de difundir trabajos de investigación, tanto clínicos como microbiológicos, referidos a la patología infecciosa, y contribuye a la formación continuada de los interesados en aquella patología mediante artículos orientados a ese fin y elaborados por autores de la mayor calificación invitados por la revista.