CO2-responsive ionic liquid for the sustainable extraction and separation of Rosa roxburghii polysaccharides

IF 7.7 1区化学 Q1 BIOCHEMISTRY & MOLECULAR BIOLOGY

International Journal of Biological Macromolecules Pub Date : 2025-03-31 DOI:10.1016/j.ijbiomac.2025.142708

Zhonghai Tang , Yunlan Chen , Changyong Cai , Shaoping Ma , Zhijian Tan

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引用次数: 0

Abstract

The extraction of Rosa roxburghii polysaccharides using conventional methods suffers from low extraction efficiency and poor selectivity. Recently, green and efficient methods of polysaccharide extraction have received increasing attention. In this study, a CO₂-responsive ionic liquid (IL) was developed for the extraction of Rosa roxburghii polysaccharides. This IL can achieve efficient extraction, and can be recycled, and reused in the extraction process. The maximum polysaccharide extraction yield of the IL was 253 mg/g under optimal single-factor experiment conditions. Three fractionated polysaccharides, RTFP-1, RTFP-2, and RTFP-3, were obtained by further purification, and their preliminary structures were characterized. RTFP-2 and RTFP-3 showed higher antioxidant and hypoglycemic activities than RTFP-1. This IL maintains high extraction efficiency after 5 cycles and reuse. This extraction method based on a CO₂-responsive IL provides an efficient and sustainable method for polysaccharide extraction.

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离子液体可持续提取分离刺梨多糖的研究

采用传统方法提取蔷薇多糖存在提取效率低、选择性差等问题。近年来，绿色高效的多糖提取方法受到越来越多的关注。本研究开发了一种二氧化碳响应离子液体（IL），用于萃取罗布麻多糖。该离子液体可实现高效提取，并可在提取过程中回收和重复使用。在最佳单因素实验条件下，IL的多糖提取率最高可达253 mg/g。通过进一步纯化，得到了 RTFP-1、RTFP-2 和 RTFP-3 三种分馏多糖，并对它们的初步结构进行了表征。与 RTFP-1 相比，RTFP-2 和 RTFP-3 表现出更高的抗氧化和降血糖活性。该萃取剂在循环使用 5 次后仍能保持较高的萃取效率。这种基于二氧化碳响应IL的萃取方法为多糖萃取提供了一种高效且可持续的方法。

本文章由计算机程序翻译，如有差异，请以英文原文为准。

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来源期刊

International Journal of Biological Macromolecules 生物-生化与分子生物学

CiteScore

13.70

自引率

9.80%

发文量

2728

审稿时长

64 days

期刊介绍： The International Journal of Biological Macromolecules is a well-established international journal dedicated to research on the chemical and biological aspects of natural macromolecules. Focusing on proteins, macromolecular carbohydrates, glycoproteins, proteoglycans, lignins, biological poly-acids, and nucleic acids, the journal presents the latest findings in molecular structure, properties, biological activities, interactions, modifications, and functional properties. Papers must offer new and novel insights, encompassing related model systems, structural conformational studies, theoretical developments, and analytical techniques. Each paper is required to primarily focus on at least one named biological macromolecule, reflected in the title, abstract, and text.