Epidemiology of Ischemic Heart Disease Burden Attributable to High Temperature in Asia From GBD 2021

Qinyi Bao MD , Zhuo Wang MD , Jian’an Wang MD, PhD , Yixin Ruan MD, PhD
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Abstract

Background

Ischemic heart disease (IHD) posed the highest global disease burden in 2021, with regional disparities in Asia. Moreover, climate change is exacerbating population exposure to high temperatures (Hi-Tem).

Objectives

This study aimed to systematically assess the burden of IHD attributed to Hi-Tem in Asia, considering geographic and demographic factors.

Methods

The Global Burden of Disease Study 2021 tools evaluated the IHD burden from Hi-Tem in Asia, and decomposition analysis was conducted to further explore the potential burden drivers.

Results

Asia witnessed a significant increase in IHD burden caused by Hi-Tem, with 88,450 (95% UI: 15,815-188,816) deaths and 2,112,025.42 (95% UI: 456,758.65-4,325,643.47) disability-adjusted life years in 2021. Over the past 3 decades, the burden increased annually by 1.63% (95% CI: 1.25%-2.01%) in age-standardized mortality rate and by 1.60% (95% CI: 1.21%-1.99%) in age-standardized rate of disability-adjusted life years. Notably, South Asia bore the heaviest burden, whereas high-income Asia Pacific had the lightest. Men and older persons consistently faced a higher IHD burden from Hi-Tem. Despite generally balanced contributions from population growth, aging, and epidemiological changes, regional disparities may persist.

Conclusions

Our study provides a comprehensive overview of the demographic and geographic characteristics of the IHD burden attributable to Hi-Tem in Asia from 1990 to 2021. In summary, Asia's IHD burden caused by Hi-Tem rose significantly, with the greater impact on men and older populations.
2021年亚洲GBD高温引起的缺血性心脏病负担的流行病学研究
2021年,非化学性心脏病(IHD)构成了全球最高的疾病负担,亚洲存在区域差异。此外,气候变化正在加剧人口暴露于高温(Hi-Tem)。本研究旨在考虑地理和人口因素,系统评估亚洲Hi-Tem引起的IHD负担。方法全球疾病负担研究2021工具评估亚洲Hi-Tem的IHD负担,并进行分解分析以进一步探索潜在的负担驱动因素。结果亚洲由Hi-Tem引起的IHD负担显著增加,2021年死亡人数为88450人(95% UI: 15815 - 188816),残疾调整生命年为2112025.42人(95% UI: 45675865 - 4325643.47)。在过去30年中,年龄标准化死亡率每年增加1.63% (95% CI: 1.25%-2.01%),残疾调整生命年的年龄标准化率每年增加1.60% (95% CI: 1.21%-1.99%)。值得注意的是,南亚的负担最重,而高收入亚太地区的负担最轻。男性和老年人始终面临着Hi-Tem带来的更高的IHD负担。尽管人口增长、老龄化和流行病学变化的贡献大致平衡,但地区差异可能持续存在。该研究提供了1990年至2021年亚洲Hi-Tem引起的IHD负担的人口统计学和地理特征的全面概述。综上所述,亚洲Hi-Tem引起的IHD负担显著上升,对男性和老年人的影响更大。
本文章由计算机程序翻译,如有差异,请以英文原文为准。
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来源期刊
JACC. Asia
JACC. Asia Cardiology and Cardiovascular Medicine
CiteScore
4.00
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