Research progress on the effects of Lycium barbarum polysaccharides in metabolic diseases

IF 3.8 2区农林科学 Q2 FOOD SCIENCE & TECHNOLOGY

Journal of Functional Foods Pub Date : 2025-04-02 DOI:10.1016/j.jff.2025.106736

Lulu Gao, Runyi Zhang, Min Zhang, Yujiao Liu, Haofeng Chai, Nana Bie, Pusen Li, Xiaomeng Liu

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Abstract

Lycium barbarum polysaccharide (LBP) stands as the primary bioactive constituent of goji berries, attracting increasing attention for its potential in mitigating metabolic disorders. This paper provides a comprehensive overview of the structure and biological properties of LBP, with particular emphasis on its roles in anti-diabetic, anti-obesity, hepatoprotective, cardiovascular protective, neuroprotective functions and protective effects on skeletal muscle. This review provides a detailed examination of the current research progress on LBPs, elucidating their mechanisms of action and clinical implications in the context of metabolic disorders. We explore the diverse bioactive components of LBPs, their effects on various metabolic parameters, and the underlying molecular mechanisms involved. Additionally, we discuss challenges and opportunities for further research to fully harness the potential of LBPs in metabolic disease management.

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来源期刊

Journal of Functional Foods FOOD SCIENCE & TECHNOLOGY-

CiteScore

9.60

自引率

1.80%

发文量

428

审稿时长

76 days

期刊介绍： Journal of Functional Foods continues with the same aims and scope, editorial team, submission system and rigorous peer review. We give authors the possibility to publish their top-quality papers in a well-established leading journal in the food and nutrition fields. The Journal will keep its rigorous criteria to screen high impact research addressing relevant scientific topics and performed by sound methodologies. The Journal of Functional Foods aims to bring together the results of fundamental and applied research into healthy foods and biologically active food ingredients. The Journal is centered in the specific area at the boundaries among food technology, nutrition and health welcoming papers having a good interdisciplinary approach. The Journal will cover the fields of plant bioactives; dietary fibre, probiotics; functional lipids; bioactive peptides; vitamins, minerals and botanicals and other dietary supplements. Nutritional and technological aspects related to the development of functional foods and beverages are of core interest to the journal. Experimental works dealing with food digestion, bioavailability of food bioactives and on the mechanisms by which foods and their components are able to modulate physiological parameters connected with disease prevention are of particular interest as well as those dealing with personalized nutrition and nutritional needs in pathological subjects.