Luong Tien Phat, Mai Thi Thao, Tran Trung Kien, Duong Thanh Tai, Peter Sandwall, Abdelmoneim Sulieman, Nissren Tamam, Sitti Yani, James C.L. Chow
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引用次数: 0
Abstract
This study investigated the dosimetric effects of varying beam numbers (9, 11, and 13) in intensity-modulated radiation therapy (IMRT) using the Halcyon linear accelerator at ShingMark University Hospital. IMRT plans for 27 patients with head-and-neck, breast, and pelvic cancers were evaluated according to the RTOG 0615 protocol, focusing on Planning Target Volume (PTV) dose coverage, uniformity, maximum and minimum doses, and Organ-at-Risk (OAR) dose constraints. For breast cancer, the 11-beam plan improved PTV coverage (V50Gy: 97.9 ± 0.5 %) and reduced maximum dose compared to 9- and 13-beam plans, while the 13-beam plan lowered heart mean dose by up to 10.5 % in left breast cases. In pelvic cases, the 13-beam plan enhanced OAR sparing, reducing bowel V35Gy by 10.5 % compared to the 9-beam plan, with minimal PTV coverage differences (<0.2 %). For head-and-neck cancer, the 13-beam plan improved PTV D95 % and spared critical structures like the brainstem, though it increased doses to the chiasm and cochlea. Treatment time and Monitor Units rose with more beams, particularly for head-and-neck and pelvic cases, but remained minimal for breast cases. These findings suggest tailoring beam numbers to cancer type and clinical priorities, balancing dosimetric benefits with treatment efficiency.
期刊介绍:
Radiation Physics and Chemistry is a multidisciplinary journal that provides a medium for publication of substantial and original papers, reviews, and short communications which focus on research and developments involving ionizing radiation in radiation physics, radiation chemistry and radiation processing.
The journal aims to publish papers with significance to an international audience, containing substantial novelty and scientific impact. The Editors reserve the rights to reject, with or without external review, papers that do not meet these criteria. This could include papers that are very similar to previous publications, only with changed target substrates, employed materials, analyzed sites and experimental methods, report results without presenting new insights and/or hypothesis testing, or do not focus on the radiation effects.