Deciphering SARS-CoV-2 evolution under antibody immune pressure.

IF 13.1 1区医学 Q1 IMMUNOLOGY

Trends in Immunology Pub Date : 2025-03-27 DOI:10.1016/j.it.2025.03.002

Fanchong Jian, Yunlong Cao

引用次数: 0

Abstract

The ongoing evolution of SARS-CoV-2 poses significant challenges to existing neutralizing antibodies and vaccines through immune escape mutations. By leveraging genomic surveillance and antibody deep mutational scanning (DMS) data, Raharinirina and colleagues developed a computational framework to elucidate region-specific SARS-CoV-2 variant dynamics and predict evolutionary trends under population immunity.

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来源期刊

Trends in Immunology 医学-免疫学

CiteScore

25.10

自引率

0.60%

发文量

130

审稿时长

6-12 weeks

期刊介绍： Trends in Immunology serves as a vital platform for tracking advancements across various areas of immunology, offering concise reviews and hypothesis-driven viewpoints in each issue. With additional sections providing comprehensive coverage, the journal offers a holistic view of immunology. This broad perspective makes it an invaluable resource for researchers, educators, and students, facilitating the connection between basic and clinical immunology. Recognized as one of the top monthly review journals in its field, Trends in Immunology is highly regarded by the scientific community.