Exposure of Spargue Dawley Rats to Phone Cell Electromagnetic Field Frequency and Related Physiological, Apoptotic and Molecular Profile of Para Oral Tissues: In-vivo Study.
{"title":"Exposure of Spargue Dawley Rats to Phone Cell Electromagnetic Field Frequency and Related Physiological, Apoptotic and Molecular Profile of Para Oral Tissues: In-vivo Study.","authors":"Gehan Abdel Naser Abdel Rahman, Aly Fahmy Mohamed","doi":"10.31557/APJCP.2025.26.3.985","DOIUrl":null,"url":null,"abstract":"<p><strong>Objective: </strong>Daily exposure to cellular EMF induced a long run deleterious impact. Accordingly, the aim of the present work is to find out the deleterious drawbacks of daily exposure of human to the cellular EMF concerning the pathological, biochemical /physiological and apoptosis profile in EM and EMF/Avocado, sole Avocado and EMF exposed /recovery group of rats.</p><p><strong>Methods: </strong>Different age (Adult, young and Senile) groups were considered. Exposure of S, A and Y rats to EMF showed elevated ROS, MDA and reduced SOD and administration of avocado customized the changes of oxidative stress. Apoptotic activity of both tongue and PG of Y, A and senile rats exposed to EMF showed age dependent response. The apoptotic effect was arranged positively as S, Y and A, revealing higher necrotic activity, Early and late apoptosis in S, Y and A rats. PG tissue showed a noticeable resistance to EMF effect.</p><p><strong>Conclusion: </strong>Also, the physiological alteration was detected insignificantly among test groups where EMF/Avocado treated groups showed almost normalization of oxidative stress compared with its values in control and EMF/Avocado and EMF recovery groups. Also, pathological changes detected in exposed groups showed the same recurrency of different tissue to normal profile.</p>","PeriodicalId":55451,"journal":{"name":"Asian Pacific Journal of Cancer Prevention","volume":"26 3","pages":"985-994"},"PeriodicalIF":0.0000,"publicationDate":"2025-03-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":"0","resultStr":null,"platform":"Semanticscholar","paperid":null,"PeriodicalName":"Asian Pacific Journal of Cancer Prevention","FirstCategoryId":"1085","ListUrlMain":"https://doi.org/10.31557/APJCP.2025.26.3.985","RegionNum":0,"RegionCategory":null,"ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":null,"EPubDate":"","PubModel":"","JCR":"Q2","JCRName":"Medicine","Score":null,"Total":0}
引用次数: 0
Abstract
Objective: Daily exposure to cellular EMF induced a long run deleterious impact. Accordingly, the aim of the present work is to find out the deleterious drawbacks of daily exposure of human to the cellular EMF concerning the pathological, biochemical /physiological and apoptosis profile in EM and EMF/Avocado, sole Avocado and EMF exposed /recovery group of rats.
Methods: Different age (Adult, young and Senile) groups were considered. Exposure of S, A and Y rats to EMF showed elevated ROS, MDA and reduced SOD and administration of avocado customized the changes of oxidative stress. Apoptotic activity of both tongue and PG of Y, A and senile rats exposed to EMF showed age dependent response. The apoptotic effect was arranged positively as S, Y and A, revealing higher necrotic activity, Early and late apoptosis in S, Y and A rats. PG tissue showed a noticeable resistance to EMF effect.
Conclusion: Also, the physiological alteration was detected insignificantly among test groups where EMF/Avocado treated groups showed almost normalization of oxidative stress compared with its values in control and EMF/Avocado and EMF recovery groups. Also, pathological changes detected in exposed groups showed the same recurrency of different tissue to normal profile.
期刊介绍:
Cancer is a very complex disease. While many aspects of carcinoge-nesis and oncogenesis are known, cancer control and prevention at the community level is however still in its infancy. Much more work needs to be done and many more steps need to be taken before effective strategies are developed. The multidisciplinary approaches and efforts to understand and control cancer in an effective and efficient manner, require highly trained scientists in all branches of the cancer sciences, from cellular and molecular aspects to patient care and palliation.
The Asia Pacific Organization for Cancer Prevention (APOCP) and its official publication, the Asia Pacific Journal of Cancer Prevention (APJCP), have served the community of cancer scientists very well and intends to continue to serve in this capacity to the best of its abilities. One of the objectives of the APOCP is to provide all relevant and current scientific information on the whole spectrum of cancer sciences. They aim to do this by providing a forum for communication and propagation of original and innovative research findings that have relevance to understanding the etiology, progression, treatment, and survival of patients, through their journal. The APJCP with its distinguished, diverse, and Asia-wide team of editors, reviewers, and readers, ensure the highest standards of research communication within the cancer sciences community across Asia as well as globally.
The APJCP publishes original research results under the following categories:
-Epidemiology, detection and screening.
-Cellular research and bio-markers.
-Identification of bio-targets and agents with novel mechanisms of action.
-Optimal clinical use of existing anti-cancer agents, including combination therapies.
-Radiation and surgery.
-Palliative care.
-Patient adherence, quality of life, satisfaction.
-Health economic evaluations.