Daily-life executive functions and bimanual performance in children with unilateral cerebral palsy.

IF 3.8 2区医学 Q1 CLINICAL NEUROLOGY

Developmental Medicine and Child Neurology Pub Date : 2025-03-28 DOI:10.1111/dmcn.16297

Alexandra Kalkantzi, Lize Kleeren, Dieter Baeyens, Lisa Decraene, Monica Crotti, Katrijn Klingels, Anja Van Campenhout, Geert Verheyden, Els Ortibus, Hilde Feys, Lisa Mailleux

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引用次数: 0

Abstract

Aim: To explore daily-life reported executive functions and their relation with bimanual performance in children with unilateral cerebral palsy (CP).

Method: In this cross-sectional study of 46 children with unilateral CP (mean age 11 years 10 months, standard deviation 2 years 10 months), executive functions were evaluated using the Behavior Rating Inventory of Executive Function (BRIEF) and bimanual performance with the Assisting Hand Assessment (AHA) and Children's Hand-use Experience Questionnaire (CHEQ). One-sample z-tests were used to compare participants' executive functions with population norms, while taking autism spectrum disorder (ASD, n = 16) as a comorbidity into account. Moreover, we used regression analysis to estimate the effect of manual ability (Manual Ability Classification System levels: I = 25, II = 15, III = 6) and having a comorbid diagnosis of ASD on executive functions (p < 0.05, R²). Lastly, non-parametric correlations (r_s, p < 0.05) were calculated between the BRIEF, CHEQ, and AHA.

Results: In general, executive functions in children with unilateral CP were poorer compared with the normative mean (p ≤ 0.024). However, when excluding participants with ASD, no difference compared with the normative mean was found. A significant effect of manual ability was found for Inhibition (p = 0.042), while ASD effects were found for most of the BRIEF subscales (p ≤ 0.001). Multiple significant correlations were found between the BRIEF and CHEQ (r_s = -0.50 to -0.29), while only the BRIEF subscale Inhibition was significantly correlated with the AHA (r_s = -0.35).

Interpretation: A higher number of children with unilateral CP exhibit difficulties in daily-life executive functions, which appear to be mainly co-occurring with ASD. Manual ability was a significant factor of inhibition-related behavioural challenges. Furthermore, there seems to be a relation between impaired executive functions and decreased bimanual performance. The findings emphasize the importance of further research, including performance-based assessments of executive functions in children with unilateral CP.

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来源期刊

Developmental Medicine and Child Neurology 医学-临床神经学

CiteScore

7.80

自引率

13.20%

发文量

338

审稿时长

3-6 weeks

期刊介绍： Wiley-Blackwell is pleased to publish Developmental Medicine & Child Neurology (DMCN), a Mac Keith Press publication and official journal of the American Academy for Cerebral Palsy and Developmental Medicine (AACPDM) and the British Paediatric Neurology Association (BPNA). For over 50 years, DMCN has defined the field of paediatric neurology and neurodisability and is one of the world’s leading journals in the whole field of paediatrics. DMCN disseminates a range of information worldwide to improve the lives of disabled children and their families. The high quality of published articles is maintained by expert review, including independent statistical assessment, before acceptance.