Relationship between frailty, as assessed using the Kihon Checklist, and falls in hemodialysis patients: a multicenter prospective cohort study.

IF 3.4 3区医学 Q2 NUTRITION & DIETETICS

Journal of Renal Nutrition Pub Date : 2025-03-27 DOI:10.1053/j.jrn.2025.03.006

Nobuyuki Shirai, Naoto Usui, Daisuke Okamura, Yoichi Sato, Sho Kojima, Kenta Mikami, Mizuki Nagashima, Yu Shimano, Nobuhito Shinozaki, Syun Hirukawa, Akihiro Sakuyama, Yoji Yamada, Masakazu Saitoh

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引用次数: 0

Abstract

Objectives: Hemodialysis (HD) patients are at a high risk of frailty, falls, and fractures. The Kihon checklist (KCL) consists of physical function, cognitive function, oral function, nutritional status, depressed mood, activities of daily living, and social participation. This study aimed to clarify the association between falls in HD patients and frailty as assessed using the KCL, as well as scores and each domain.

Methods: A multicenter prospective cohort study was conducted across nine facilities. Frailty was assessed using the KCL. Falls were then monitored for one year. Participants were classified into three groups based on their KCL scores: robust, pre-frailty, and frailty. In the logistic regression analysis, the dependent variables were falls, severe falls, or fractures, whereas the independent variables were group classification, KCL score, or each domain.

Results: A total of 403 HD patients (70.0 [60.0-76.0] years, 170 [42.1%] women) were analyzed. During the 1-year follow-up period, 117 (29.0%) patients experienced falls. Pre-frailty (OR 3.00, 95%CI 1.17-7.71, p < 0.001) and frailty (OR 6.79, 95%CI 2.69-17.16, p < 0.001) were independently associated with falls compared with robust patients. Additionally, the KCL score was associated with severe falls (OR 1.15, 95%CI 1.06 - 1.25, p = 0.001) and fracture (OR 1.13, 95%CI 1.01-1.28, p = 0.04). By KCL domain, physical function (OR 3.46, 95%CI 2.06-5.83, p < 0.001) and cognitive function (OR 1.74, 95%CI 1.09-2.77, p = 0.02) were independently associated with falls.

Conclusions: The KCL may be a useful screening tool for estimating fall and fracture risk in this population.

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来源期刊

Journal of Renal Nutrition 医学-泌尿学与肾脏学

CiteScore

5.70

自引率

12.50%

发文量

146

审稿时长

6.7 weeks

期刊介绍： The Journal of Renal Nutrition is devoted exclusively to renal nutrition science and renal dietetics. Its content is appropriate for nutritionists, physicians and researchers working in nephrology. Each issue contains a state-of-the-art review, original research, articles on the clinical management and education of patients, a current literature review, and nutritional analysis of food products that have clinical relevance.