Incidence and Risk Factors of In-Hospital Gastrointestinal-Related Complications Following Bariatric Surgery: A Retrospective Nationwide Inpatient Sample Database Study.
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Abstract
Background: Obesity is associated with numerous serious physiological and psychological health problems. Bariatric surgery (BS) remains the most effective treatment for obesity, but early postoperative gastrointestinal complications may require additional surgical intervention. The objective of this study was to analyze gastrointestinal-related complications (GRCs) and their risk factors following BS, including sleeve gastrectomy (SG) and Roux-en-Y gastric bypass (RYGB), using a nationwide database.
Methods: An analysis of the Nationwide Inpatient Sample data from 2010 to 2019 was conducted to compare patients following BS with versus without postoperative GRCs. Variables included demographics, hospital characteristics, length of stay, costs, comorbidities, and complications. Risk factors were identified through stepwise multivariate logistic regression.
Results: Among 323,066 BS patients, 12,248 (3.79%) developed GRCs, with a decreasing trend observed over the study period. Common complications included gastrointestinal bleeding (1.37%), bowel obstruction (1.84%), and anastomotic issues (0.99%). Significant risk factors included advanced age, anemia (deficiency and chronic blood loss), cardiovascular conditions (heart failure, valve disease, peripheral vascular disorders), coagulation abnormalities, rheumatoid arthritis or collagen vascular diseases, drug abuse, electrolyte imbalances, neurological conditions, renal failure, non-bleeding peptic ulcer disease, and weight loss. Interestingly, liver disease emerged as a risk factor for GRCs after SG while acting as a protective factor for GRCs after RYGB.
Conclusion: Understanding the risk factors for GRCs after BS would allow for improved patient management and clinical outcomes.
期刊介绍：
Obesity Surgery is the official journal of the International Federation for the Surgery of Obesity and metabolic disorders (IFSO). A journal for bariatric/metabolic surgeons, Obesity Surgery provides an international, interdisciplinary forum for communicating the latest research, surgical and laparoscopic techniques, for treatment of massive obesity and metabolic disorders. Topics covered include original research, clinical reports, current status, guidelines, historical notes, invited commentaries, letters to the editor, medicolegal issues, meeting abstracts, modern surgery/technical innovations, new concepts, reviews, scholarly presentations and opinions.
Obesity Surgery benefits surgeons performing obesity/metabolic surgery, general surgeons and surgical residents, endoscopists, anesthetists, support staff, nurses, dietitians, psychiatrists, psychologists, plastic surgeons, internists including endocrinologists and diabetologists, nutritional scientists, and those dealing with eating disorders.
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