Risk of post-ERCP pancreatitis due to placement of biliary self-expandable metal stents (SEMS): a single-center retrospective study.

IF 6.7 1区医学 Q1 GASTROENTEROLOGY & HEPATOLOGY

Gastrointestinal endoscopy Pub Date : 2025-03-26 DOI:10.1016/j.gie.2025.03.1212

Mark Radetic, Michael Ladna, Steve Shen, Arvin Daneshmand, Talal Seoud, Devika Dixit, Amira Qumseya, Aleksey Novikov, Bashar Qumseya

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引用次数: 0

Abstract

Background & aims: Post-ERCP pancreatitis (PEP) is the most common adverse event following ERCP. Placement of self-expandable metal stents (SEMS) is common during ERCP. Our aim was to investigate whether SEMS placement during ERCP increases the risk for PEP.

Methods: We conducted a retrospective study on patients who underwent ERCP at our institution from 2016 to 2021. Patients were divided into those with SEMS and those without SEMS. The PEP rates were compared between the two groups. We used a multivariable logistic regression model to assess the strength of the association between the primary outcome (PEP) and its predictor (SEMS placement) while controlling for potential confounders such as procedure indication, indomethacin use, native papilla, and pancreatic duct manipulation/stenting.

Results: 1,718 consecutive patients were included in the study with 21% (n=358) undergoing SEMS placement. PEP was higher in the SEMS group than in the non-SEMS group (10.6% vs. 5.7%, p=0.0008) and higher than those who had plastic stent placement (10.6% vs. 6.3%, n=31/494; p=0.0299). On multivariable logistic regression analysis, SEMS placement was independently associated with a 2.3-fold increased risk of PEP (adjusted OR 2.30 [95% CI: 1.48-3.56], p=0.0002.

Conclusions: At our center, SEMS placement was found to be an independent risk factor for the development of PEP.

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来源期刊

Gastrointestinal endoscopy 医学-胃肠肝病学

CiteScore

10.30

自引率

7.80%

发文量

1441

审稿时长

38 days

期刊介绍： Gastrointestinal Endoscopy is a journal publishing original, peer-reviewed articles on endoscopic procedures for studying, diagnosing, and treating digestive diseases. It covers outcomes research, prospective studies, and controlled trials of new endoscopic instruments and treatment methods. The online features include full-text articles, video and audio clips, and MEDLINE links. The journal serves as an international forum for the latest developments in the specialty, offering challenging reports from authorities worldwide. It also publishes abstracts of significant articles from other clinical publications, accompanied by expert commentaries.