Incidence of loss to follow-up and associated factors among mothers on antiretroviral therapy in the context of elimination of mother-to-child transmission of HIV in two health districts of Bobo-Dioulasso in Burkina Faso.

IF 2.4 3区医学 Q2 OBSTETRICS & GYNECOLOGY

BMC Women's Health Pub Date : 2025-03-29 DOI:10.1186/s12905-025-03658-7

Béninwendé Léticia Delphine Sakana, Ziemlé Clément Meda, Bernard Ilboudo, Abdoulaye Ouattara, Blahima Konate, Bernard Eric Dabone, Manitu Serge Mayaka, Gueswendé Léon Savadogo, Philippe Van De Perre

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引用次数: 0

Abstract

Introduction: Since 2017, Burkina Faso has rolled out a plan to eliminate vertical transmission of HIV (eMTCT). Elimination will only be achieved when mothers have regular follow-up and good compliance with antiretroviral therapy (ART). The aim of this article is to study the incidence and associated factors for loss to follow-up (LTFU ), in women living with HIV (WLHIV) monitored as part of the eMTCT.

Methods: This study consisted of a retrospective analysis of routinely collected data from pregnant women who were screened and initiated ART in the Do and Dafra health districts of Bobo-Dioulasso between 2017 and 2020 as part of the eMTCT. The study ran from May 2023 to March 2024. The Kaplan-Meier model was used to estimate the rate of LTFU; the Cox model was used for identification of factors associated with LTFU and verification of Kaplan-Meier results.

Results: Three hundred and four newly diagnosed pregnant WLHIV were included in this study. The median age of the mothers was 30 [24; 36] years. The incidence of LTFU was 22.9 per 100 person-years. Younger age (HR = 2.40; 95%CI: 1.37-4.20) was associated with a higher incidence of LTFU, whereas urban residence (HR = 0.57; 95%CI: 0.39-0.85), in contrast to rural residence, was associated with a lower incidence of LTFU.

Conclusion: The study showed a high incidence of LTFU, associated with younger age and rural residence, in the eMTCT programme in Burkina Faso.

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布基纳法索Bobo-Dioulasso两个卫生区在消除艾滋病毒母婴传播的背景下，接受抗逆转录病毒治疗的母亲的随访损失发生率及相关因素。

自2017年以来，布基纳法索推出了一项消除艾滋病毒垂直传播（eMTCT）的计划。只有在母亲定期随访并良好遵守抗逆转录病毒治疗（ART）的情况下，才能实现消除。本文的目的是研究作为eMTCT的一部分监测的艾滋病毒感染者（WLHIV）的发生率和随访损失（LTFU）的相关因素。方法：本研究包括对2017年至2020年期间在Bobo-Dioulasso的Do和Dafra卫生区接受筛查并开始抗逆转录病毒治疗的孕妇常规收集的数据进行回顾性分析，作为eMTCT的一部分。这项研究从2023年5月持续到2024年3月。采用Kaplan-Meier模型估计LTFU的发生率；采用Cox模型识别与LTFU相关的因素并验证Kaplan-Meier结果。结果：本研究纳入了新诊断的妊娠WLHIV患者340例。母亲年龄中位数为30岁[24岁；36年。LTFU的发生率为22.9 / 100人年。年龄较小(HR = 2.40；95%CI: 1.37-4.20)与LTFU的高发病率相关，而城市居住(HR = 0.57；95%CI: 0.39-0.85)，与农村居民相比，与较低的LTFU发生率相关。结论：该研究表明，在布基纳法索的eMTCT项目中，LTFU的发病率较高，与年龄较小和农村居住有关。

本文章由计算机程序翻译，如有差异，请以英文原文为准。

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来源期刊

BMC Women's Health OBSTETRICS & GYNECOLOGY-

CiteScore

3.40

自引率

4.00%

发文量

444

审稿时长

>12 weeks

期刊介绍： BMC Women''s Health is an open access, peer-reviewed journal that considers articles on all aspects of the health and wellbeing of adolescent girls and women, with a particular focus on the physical, mental, and emotional health of women in developed and developing nations. The journal welcomes submissions on women''s public health issues, health behaviours, breast cancer, gynecological diseases, mental health and health promotion.