Prevalence of Pentatrichomonas hominis infection in wild rodents.

IF 2.3 2区农林科学 Q1 VETERINARY SCIENCES

BMC Veterinary Research Pub Date : 2025-03-28 DOI:10.1186/s12917-025-04604-3

Yan Tang, Hai-Tao Wang, Jing-Hao Li, Qing-Yu Hou, Si-Yuan Qin, He Ma, Ya Qin, Quan Zhao, Hany M Elsheikha, Shuo Liu

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引用次数: 0

Abstract

Background: Pentatrichomonas hominis is a zoonotic pathogen linked to gastrointestinal diseases in various animal species and humans. However, its prevalence of in wild rodents remains unexplored. Therefore, investigating the prevalence and molecular characteristics of P. hominis in wild rodents is essential.

Methods: M. Replace the crossed out sentence above with the following version:This study assessed the prevalence of P. hominis in wild rodents by analyzing 510 fecal samples using nested PCR. Statistical analysis of risk factors was performed with SAS (v9.0) and SPSS software.

Results: The infection rates were 18.18% (16/88) in Yunnan, 0.94% (3/319) in Hunan, and 0% (0/103) in Guangxi. Among the species, Rattus rattus sladeni had the highest infection rate at 40% (2/5), followed by R. flavipectus at 23.08% (9/39), while Niviventer lotipes (0%, 0/23) and R. losea (0%, 0/41) showed no infection. Seasonally, the highest prevalence was observed in autumn (18.18%, 16/88) and the lowest in winter (0%, 0/103). Rodents from farmland had significantly higher infection rates than mountain areas (0%, 0/103) and lakeshores (0.32%, 1/312). Although female rodents had a higher infection rate (4.62%, 11/238) compared to males (2.94%, 8/272), the difference was not statistically significant. Phylogenetic analysis revealed that all P. hominis strains identified belonged to the zoonotic CC1 genotype.

Conclusions: This study is the first to describe the distribution of P. hominis in wild rodents, paving the way for further epidemiological research on this parasite in wild animals. Such research is crucial for developing strategies to protect human health from zoonotic threats from wild rodents.

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野生啮齿动物人五毛单胞菌感染流行情况。

背景：人五毛单胞菌是一种与多种动物和人类胃肠道疾病相关的人畜共患病原体。然而，其在野生啮齿动物中的流行程度尚未探明。因此，研究人源弓形虫在野生啮齿动物中的流行和分子特征是十分必要的。本研究采用巢式PCR法对510份野生啮齿动物粪便样本进行分析，评估了人疟原虫在野生啮齿动物中的流行情况。采用SAS （v9.0）和SPSS软件对危险因素进行统计分析。结果：云南省感染率为18.18%(16/88)，湖南省为0.94%(3/319)，广西为0%（0/103）。其中，褐家鼠感染率最高，为40%(2/5)，黄胸鼠次之，为23.08%(9/39)，褐家鼠（0%,0/23）和黄胸鼠（0%,0/41）均未感染。季节上，秋季患病率最高（18.18%,16/88），冬季最低（0%,0/103）。农田鼠类感染率显著高于山区（0%,0/103）和湖滨（0.32%,1/312）。雌性鼠感染率（4.62%,11/238）高于雄性鼠（2.94%,8/272），但差异无统计学意义。系统发育分析表明，所有鉴定的人疟原虫属人畜共患病CC1基因型。结论：本研究首次描述了人弓形虫在野生啮齿动物中的分布，为进一步开展该寄生虫在野生动物中的流行病学研究奠定了基础。这类研究对于制定保护人类健康免受野生啮齿动物人畜共患病威胁的战略至关重要。

本文章由计算机程序翻译，如有差异，请以英文原文为准。

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来源期刊

BMC Veterinary Research VETERINARY SCIENCES-

CiteScore

4.80

自引率

3.80%

发文量

420

审稿时长

3-6 weeks

期刊介绍： BMC Veterinary Research is an open access, peer-reviewed journal that considers articles on all aspects of veterinary science and medicine, including the epidemiology, diagnosis, prevention and treatment of medical conditions of domestic, companion, farm and wild animals, as well as the biomedical processes that underlie their health.