A national survey of suicidality and non-suicidal self-injury in bipolar disorder: insights from network analysis.

IF 3.4 2区 医学 Q2 PSYCHIATRY
Lvchun Cui, Yuncheng Zhu, Yang Li, Jia Zhou, Guiyun Xu, Miao Pan, Zhiyu Chen, Wenfei Li, Zhian Jiao, Mingli Li, Yong Zhang, Jingxu Chen, Xiuzhe Chen, Na Li, Jing Sun, Jian Zhang, Shaohua Hu, Haishan Wu, Zhaoyu Gan, Yan Qin, Yumei Wang, Yantao Ma, Xiaoping Wang, Xiaohong Li, Chuangxin Wu, Yiyun Cai, Jiaye Chen, Baichuan Wu, Zuowei Wang, Daihui Peng, Yiru Fang
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引用次数: 0

Abstract

Background: There is a high prevalence of suicidal ideation (SI), suicide attempts (SA), and non-suicidal self-injury (NSSI) in bipolar disorder (BD). Understanding the nature of suicidality and NSSI in BD is an important way to inform optimal intervention for reducing suicide risk. We aimed to investigate the prevalence and correlates of SI, SA, and NSSI in patients with BD using data from a national survey. We used network analysis to explore the associations among suicidality, NSSI, addictive features of NSSI, and symptoms of BD.

Methods: Participants with BD were recruited from 20 research centers in China. Suicidality, NSSI, addictive features, and symptoms of BD were measured via a standardized electronic case report form. We used logistic regression and network analysis for data analysis.

Results: Of the 1,055 participants recruited, over 50% with depressive or mixed episodes had SI, more than 20% engaged in SA, and over 40% reported NSSI. The polarity of mood episodes was independently associated with SI ([hypo]mania vs. mixed episodes: odds ratio [OR] = 0.22, 95% confidence interval [CI] 0.14-0.33, p < 0.001) and NSSI ([hypo]mania vs. mixed episodes: OR = 0.33, 95% CI 0.19-0.58, p < 0.001; depressive episodes vs. mixed episodes: OR = 0.59, 95% CI 0.35-0.98, p = 0.040). Participants with mixed episodes reported the most severe addictive features of NSSI. SI was the most influential symptom within the network model of the total sample; NSSI, SI, and depressive symptoms were identified as key "bridge symptoms".

Conclusions: Suicidality and NSSI in BD were closely associated with depressive and mixed episodes, with mixed episodes showing the highest prevalence of NSSI and the most pronounced addictive features. SI was identified as the central symptom within the self-harm network, emphasizing its importance as an intervention target. These findings could offer potential insights regarding suicidality and NSSI in BD that can inform intervention strategies.

双相情感障碍中自杀和非自杀自伤的全国调查:来自网络分析的见解。
背景:双相情感障碍(BD)患者中自杀意念(SI)、自杀企图(SA)和非自杀性自伤(NSSI)的发生率较高。了解双相障碍中自杀和自伤的本质是降低自杀风险的最佳干预措施的重要途径。我们的目的是利用一项全国调查的数据,调查BD患者中SI、SA和自伤的患病率及其相关性。本研究采用网络分析方法探讨自杀、自伤、自伤成瘾特征与双相障碍症状之间的关系。方法:从中国20个研究中心招募双相障碍患者。自杀倾向、自伤、成瘾特征和双相障碍症状通过标准化的电子病例报告表格进行测量。我们使用逻辑回归和网络分析进行数据分析。结果:在招募的1055名参与者中,超过50%的抑郁或混合发作者有自伤,超过20%的人从事SA,超过40%的人报告自伤。情绪发作的极性与自伤独立相关([低]躁狂与混合发作:比值比[OR] = 0.22, 95%可信区间[CI] 0.14-0.33, p)结论:双相障碍患者的自杀倾向和自伤与抑郁和混合发作密切相关,混合发作表现出最高的自伤患病率和最明显的成瘾特征。自伤是自我伤害网络中的中心症状,强调了其作为干预目标的重要性。这些发现可能为双相障碍的自杀和自伤提供潜在的见解,从而为干预策略提供信息。
本文章由计算机程序翻译,如有差异,请以英文原文为准。
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来源期刊
BMC Psychiatry
BMC Psychiatry 医学-精神病学
CiteScore
5.90
自引率
4.50%
发文量
716
审稿时长
3-6 weeks
期刊介绍: BMC Psychiatry is an open access, peer-reviewed journal that considers articles on all aspects of the prevention, diagnosis and management of psychiatric disorders, as well as related molecular genetics, pathophysiology, and epidemiology.
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