Effect of calcium and calcium-fluoride phytate as active fillers in dental resin-based composites on chemical and physical properties

IF 4.6 1区医学 Q1 DENTISTRY, ORAL SURGERY & MEDICINE

Dental Materials Pub Date : 2025-03-27 DOI:10.1016/j.dental.2025.03.010

Zuzanna Buchwald , Aleksandra Domke , Marcel Jakubowski , Maria Ratajczak , Tomasz Buchwald , Mutlu Özcan , Adam Voelkel , Mariusz Sandomierski

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引用次数: 0

Abstract

Objectives

This study aims to synthesize, characterize, and evaluate calcium phytate (Ca-PA) and fluorinated calcium phytate (Ca-PA-F) as novel active fillers in resin-based dental composites (RBCs). The hypothesis assumes that these fillers will provide remineralization potential through calcium and fluoride ion release while maintaining satisfactory physicochemical properties.

Methods

Ca-PA and Ca-PA-F fillers were synthesized, characterized using various spectroscopic and microscopic techniques, and incorporated into methacrylate-based RBCs at a filler fraction of 65 vol% (≈30 wt%). The composites were polymerized and evaluated for degree of conversion (DC), depth of cure (DOC), polymerization shrinkage (PS), mechanical properties (compressive strength [CS], flexural strength [FS]), water sorption (SP), solubility (SL), also after 35 days of incubation, color, opacity, and calcium and fluoride release over 35 days in saline.

Results

Both experimental composites exhibited high DC (>70 %), DOC (>3 mm), and moderate PS (4.18–6.19 %). Ca-PA-c showed superior CS (351.6 MPa) and FS (53.9 MPa), while Ca-PA-F-c had lower CS (246.3 MPa) and FS (43.5 MPa). Excessive SP (>40 µg·mm⁻³) and high SL after 35 days of incubation, especially for Ca-PA-F-c, were observed. Both materials released calcium ions, with Ca-PA-F-c also releasing fluoride, showing the remineralizing potential.

Significance

Phytate-based fillers provide a promising alternative for RBCs with remineralization potential. However, improvements in filler dispersion, flexural strength, and long-term mass stability are needed. Future work should focus on filler silanization or hybridization with conventional fillers to enhance mechanical performance while maintaining the ability to ions release.

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来源期刊

Dental Materials 工程技术-材料科学：生物材料

CiteScore

9.80

自引率

10.00%

发文量

290

审稿时长

67 days

期刊介绍： Dental Materials publishes original research, review articles, and short communications. Academy of Dental Materials members click here to register for free access to Dental Materials online. The principal aim of Dental Materials is to promote rapid communication of scientific information between academia, industry, and the dental practitioner. Original Manuscripts on clinical and laboratory research of basic and applied character which focus on the properties or performance of dental materials or the reaction of host tissues to materials are given priority publication. Other acceptable topics include application technology in clinical dentistry and dental laboratory technology. Comprehensive reviews and editorial commentaries on pertinent subjects will be considered.