Effect of calcium and calcium-fluoride phytate as active fillers in dental resin-based composites on chemical and physical properties

IF 4.6 1区医学 Q1 DENTISTRY, ORAL SURGERY & MEDICINE

Dental Materials Pub Date : 2025-03-27 DOI:10.1016/j.dental.2025.03.010

Zuzanna Buchwald , Aleksandra Domke , Marcel Jakubowski , Maria Ratajczak , Tomasz Buchwald , Mutlu Özcan , Adam Voelkel , Mariusz Sandomierski

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引用次数: 0

Abstract

Objectives

This study aims to synthesize, characterize, and evaluate calcium phytate (Ca-PA) and fluorinated calcium phytate (Ca-PA-F) as novel active fillers in resin-based dental composites (RBCs). The hypothesis assumes that these fillers will provide remineralization potential through calcium and fluoride ion release while maintaining satisfactory physicochemical properties.

Methods

Ca-PA and Ca-PA-F fillers were synthesized, characterized using various spectroscopic and microscopic techniques, and incorporated into methacrylate-based RBCs at a filler fraction of 65 vol% (≈30 wt%). The composites were polymerized and evaluated for degree of conversion (DC), depth of cure (DOC), polymerization shrinkage (PS), mechanical properties (compressive strength [CS], flexural strength [FS]), water sorption (SP), solubility (SL), also after 35 days of incubation, color, opacity, and calcium and fluoride release over 35 days in saline.

Results

Both experimental composites exhibited high DC (>70 %), DOC (>3 mm), and moderate PS (4.18–6.19 %). Ca-PA-c showed superior CS (351.6 MPa) and FS (53.9 MPa), while Ca-PA-F-c had lower CS (246.3 MPa) and FS (43.5 MPa). Excessive SP (>40 µg·mm⁻³) and high SL after 35 days of incubation, especially for Ca-PA-F-c, were observed. Both materials released calcium ions, with Ca-PA-F-c also releasing fluoride, showing the remineralizing potential.

Significance

Phytate-based fillers provide a promising alternative for RBCs with remineralization potential. However, improvements in filler dispersion, flexural strength, and long-term mass stability are needed. Future work should focus on filler silanization or hybridization with conventional fillers to enhance mechanical performance while maintaining the ability to ions release.

查看原文本刊更多论文

植酸钙和氟化钙作为活性填料对牙用树脂基复合材料理化性能的影响。

目的：本研究旨在合成、表征和评价植酸钙（Ca-PA）和氟化植酸钙（Ca-PA- f）作为树脂基牙科复合材料（rbc）的新型活性填料。该假设认为，这些填料将通过释放钙和氟离子提供再矿化潜力，同时保持令人满意的物理化学性质。方法：合成Ca-PA和Ca-PA- f填料，利用各种光谱和显微技术对其进行表征，并以65 vol%（≈30 wt%）的填料掺入甲基丙烯酸酯基红细胞中。对复合材料进行聚合，并对其转化度（DC）、固化深度（DOC）、聚合收缩率（PS）、力学性能（抗压强度[CS]、抗折强度[FS]）、吸水性（SP）、溶解度（SL）、35天后的颜色、不透明度以及在盐水中35天内钙和氟化物的释放进行评估。结果：两种复合材料均具有高DC（>70 %）、DOC（>3 mm）和中等PS（4.18-6.19 %）。Ca-PA-c具有较好的CS（351.6 MPa）和FS(53.9 MPa)， Ca-PA-F-c具有较低的CS（246.3 MPa）和FS（43.5 MPa）。培养35天后，观察到过量的SP （bbb40 µg·mm⁻³）和高SL，特别是Ca-PA-F-c。两种材料都释放钙离子，Ca-PA-F-c也释放氟化物，显示出再矿化潜力。意义：植酸基填充物为具有再矿化潜力的红细胞提供了一种很有前途的替代品。然而，填料分散性、抗弯强度和长期质量稳定性需要改进。未来的工作应集中在填料硅化或与传统填料杂化，以提高机械性能，同时保持离子释放能力。

本文章由计算机程序翻译，如有差异，请以英文原文为准。

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来源期刊

Dental Materials 工程技术-材料科学：生物材料

CiteScore

9.80

自引率

10.00%

发文量

290

审稿时长

67 days

期刊介绍： Dental Materials publishes original research, review articles, and short communications. Academy of Dental Materials members click here to register for free access to Dental Materials online. The principal aim of Dental Materials is to promote rapid communication of scientific information between academia, industry, and the dental practitioner. Original Manuscripts on clinical and laboratory research of basic and applied character which focus on the properties or performance of dental materials or the reaction of host tissues to materials are given priority publication. Other acceptable topics include application technology in clinical dentistry and dental laboratory technology. Comprehensive reviews and editorial commentaries on pertinent subjects will be considered.