Jingwen Dong, Weiwei Li, Yang Yang, Song Liu, Yilin Li, Yuling Meng, Weixing Shan
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引用次数: 0
Abstract
Papain-like cysteine proteases (PLCPs) are pivotal in plant development and immunity, though their specific regulatory mechanisms in immune responses remain largely unexplored. In this study, we identify AtRD19C, a vacuole-localized PLCP, and demonstrate its role in negatively regulating plant immunity to Phytophthora parasitica. We show that AtRD19C suppresses the ethylene (ET) signaling pathway by destabilizing the copper chaperone AtATX1, which is essential for activating ET signaling through the ethylene receptor ETR1. Genetic and biochemical analyses reveal that AtATX1 and the ET signaling pathway positively regulate immunity against Phytophthora. Given the conserved roles of RD19C and ATX1 in Solanum tuberosum, our findings suggest a conserved mechanism by which RD19C and ATX1 regulate resistance to Phytophthora across plant species.
期刊介绍：
Publishing the best original research papers in all key areas of modern plant biology from the world"s leading laboratories, The Plant Journal provides a dynamic forum for this ever growing international research community.
Plant science research is now at the forefront of research in the biological sciences, with breakthroughs in our understanding of fundamental processes in plants matching those in other organisms. The impact of molecular genetics and the availability of model and crop species can be seen in all aspects of plant biology. For publication in The Plant Journal the research must provide a highly significant new contribution to our understanding of plants and be of general interest to the plant science community.
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