Metabolic engineering of lipids for crop resilience and nutritional improvements towards sustainable agriculture

IF 3.9 4区生物学 Q1 GENETICS & HEREDITY

Functional & Integrative Genomics Pub Date : 2025-04-01 DOI:10.1007/s10142-025-01588-z

Swati Mangla, Yogesh K. Ahlawat, Gaurav Pathak, Nisha Sharma, Maryam Samani, Veer Bhan, Jemaa Essemine, Yashirdisai Sampasivam, Navjot Singh Brar, Anurag Malik, Vikas Ramteke, Shivali Gupta, Sumati Choubey

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引用次数: 0

Abstract

Metabolic engineering of lipids in crops presents a promising strategy to enhance resilience against environmental stressors while improving nutritional quality. By manipulating key enzymes in lipid metabolism, introducing novel genes, and utilizing genome editing technologies, researchers have improved crop tolerance to abiotic stresses such as drought, salinity, and extreme temperatures. Additionally, modified lipid pathways contribute to resistance against biotic stresses, including pathogen attacks and pest infestations. Engineering multiple stress-resistance traits through lipid metabolism offers a holistic approach to strengthening crop resilience amid changing environmental conditions. Beyond stress tolerance, lipid engineering enhances the nutritional profile of crops by increasing beneficial lipids such as omega-3 fatty acids, vitamins, and antioxidants. This dual approach not only improves crop yield and quality but also supports global food security by ensuring sustainable agricultural production. Integrating advanced biotechnological tools with a deeper understanding of lipid biology paves the way for developing resilient, nutrient-rich crops capable of withstanding climate change and feeding a growing population.

Graphical Abstract

The diagram depicts how the metabolic engineering of lipids enhances crop resilience by improving stress tolerance, increases nutritional value through enrichment of essential FAs, and facilitates waste-to-energy conversion by optimizing lipid profiles for biofuel production. This integrated approach promotes sustainable agricultural practices and resource efficiency which in turn satisfies our Sustainable development goals viz. 2,3,12, 7.

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脂质代谢工程对作物抗逆性和可持续农业营养改善的影响

作物脂质代谢工程是提高作物抗环境胁迫能力、改善营养品质的有效途径。通过控制脂质代谢中的关键酶、引入新基因和利用基因组编辑技术，研究人员提高了作物对干旱、盐度和极端温度等非生物胁迫的耐受性。此外，修饰的脂质途径有助于抵抗生物胁迫，包括病原体攻击和害虫侵袭。通过脂质代谢来设计多种抗逆性性状，为增强作物在变化环境条件下的抗逆性提供了一种全面的途径。除了抗逆性外，脂质工程还通过增加有益的脂质，如ω -3脂肪酸、维生素和抗氧化剂，提高了作物的营养成分。这种双重方法不仅提高了作物产量和质量，而且通过确保可持续农业生产支持全球粮食安全。将先进的生物技术工具与对脂质生物学的更深入了解相结合，为开发能够抵御气候变化并养活不断增长的人口的有弹性、营养丰富的作物铺平了道路。图表摘要：该图描述了脂质代谢工程如何通过提高抗逆性来增强作物的抗逆性，通过富集必需脂肪酸来增加营养价值，并通过优化生物燃料生产的脂质谱来促进废物转化为能源。这种综合方法促进可持续农业实践和资源效率，从而满足我们的可持续发展目标2、3、12、7。

本文章由计算机程序翻译，如有差异，请以英文原文为准。

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来源期刊

Functional & Integrative Genomics 生物-遗传学

CiteScore

3.50

自引率

3.40%

发文量

审稿时长

2 months

期刊介绍： Functional & Integrative Genomics is devoted to large-scale studies of genomes and their functions, including systems analyses of biological processes. The journal will provide the research community an integrated platform where researchers can share, review and discuss their findings on important biological questions that will ultimately enable us to answer the fundamental question: How do genomes work?