Metabolic engineering of lipids for crop resilience and nutritional improvements towards sustainable agriculture

IF 3.9 4区生物学 Q1 GENETICS & HEREDITY

Functional & Integrative Genomics Pub Date : 2025-04-01 DOI:10.1007/s10142-025-01588-z

Swati Mangla, Yogesh K. Ahlawat, Gaurav Pathak, Nisha Sharma, Maryam Samani, Veer Bhan, Jemaa Essemine, Yashirdisai Sampasivam, Navjot Singh Brar, Anurag Malik, Vikas Ramteke, Shivali Gupta, Sumati Choubey

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引用次数: 0

Abstract

Metabolic engineering of lipids in crops presents a promising strategy to enhance resilience against environmental stressors while improving nutritional quality. By manipulating key enzymes in lipid metabolism, introducing novel genes, and utilizing genome editing technologies, researchers have improved crop tolerance to abiotic stresses such as drought, salinity, and extreme temperatures. Additionally, modified lipid pathways contribute to resistance against biotic stresses, including pathogen attacks and pest infestations. Engineering multiple stress-resistance traits through lipid metabolism offers a holistic approach to strengthening crop resilience amid changing environmental conditions. Beyond stress tolerance, lipid engineering enhances the nutritional profile of crops by increasing beneficial lipids such as omega-3 fatty acids, vitamins, and antioxidants. This dual approach not only improves crop yield and quality but also supports global food security by ensuring sustainable agricultural production. Integrating advanced biotechnological tools with a deeper understanding of lipid biology paves the way for developing resilient, nutrient-rich crops capable of withstanding climate change and feeding a growing population.

Graphical Abstract

The diagram depicts how the metabolic engineering of lipids enhances crop resilience by improving stress tolerance, increases nutritional value through enrichment of essential FAs, and facilitates waste-to-energy conversion by optimizing lipid profiles for biofuel production. This integrated approach promotes sustainable agricultural practices and resource efficiency which in turn satisfies our Sustainable development goals viz. 2,3,12, 7.

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来源期刊

Functional & Integrative Genomics 生物-遗传学

CiteScore

3.50

自引率

3.40%

发文量

审稿时长

2 months

期刊介绍： Functional & Integrative Genomics is devoted to large-scale studies of genomes and their functions, including systems analyses of biological processes. The journal will provide the research community an integrated platform where researchers can share, review and discuss their findings on important biological questions that will ultimately enable us to answer the fundamental question: How do genomes work?