Comparative evaluation of ozonized water versus normal saline irrigation with mechanical debridement in chronic periodontitis patients – A clinical study

Q1 Medicine

Journal of oral biology and craniofacial research Pub Date : 2025-03-31 DOI:10.1016/j.jobcr.2025.03.014

Rohith G.N. , Nayana Patel , Rita Jha , Radha Vachhani , Nisha Verlianey , Ankit Sant

{"title":"Comparative evaluation of ozonized water versus normal saline irrigation with mechanical debridement in chronic periodontitis patients – A clinical study","authors":"Rohith G.N. , Nayana Patel , Rita Jha , Radha Vachhani , Nisha Verlianey , Ankit Sant","doi":"10.1016/j.jobcr.2025.03.014","DOIUrl":null,"url":null,"abstract":"<div><h3>Background</h3><div>Ozone therapy is a rather novel approach for managing many diseases, encompassing oral disorders such as tooth caries and periodontal disease. It possesses the ability to disrupt microbial cell walls, resulting in rapid cell lysis. Moreover, characteristics of ozone such as anti-inflammation, stimulation and modulation of immunity contribute to mitigating the host response aspect of periodontal disease.</div></div><div><h3>Objective</h3><div>To assess the adjunctive advantages of irrigation of ozonized water in conjunction with mechanical debridement for the treatment of periodontitis.</div></div><div><h3>Methodology</h3><div>50 patients with chronic periodontitis and pocket probing depth ≥4 have been divided into 2 groups i.e. Test (n = 25) and control groups (n = 25). While the control group was administered normal saline irrigation and mechanical debridement, the test group was given ozonized water irrigation. Evaluations were conducted at baseline and four weeks following treatment to determine the plaque score, bleeding score, pocket probing depth, and clinical attachment level.</div></div><div><h3>Results</h3><div>Clinical measures such as clinical attachment level, pocket probing depth, bleeding index, and plaque index, significantly improved with adjunctive ozone water irrigation. The frequency of sites with bleeding on probing that had a pocket depth ≥4 mm was significantly reduced as a result of ozone water irrigation.</div></div><div><h3>Conclusion</h3><div>Ozone irrigation alongside nonsurgical periodontal therapy offers adjunctive benefits by reducing clinical parameters.</div></div>","PeriodicalId":16609,"journal":{"name":"Journal of oral biology and craniofacial research","volume":"15 3","pages":"Pages 594-599"},"PeriodicalIF":0.0000,"publicationDate":"2025-03-31","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":"0","resultStr":null,"platform":"Semanticscholar","paperid":null,"PeriodicalName":"Journal of oral biology and craniofacial research","FirstCategoryId":"1085","ListUrlMain":"https://www.sciencedirect.com/science/article/pii/S2212426825000776","RegionNum":0,"RegionCategory":null,"ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":null,"EPubDate":"","PubModel":"","JCR":"Q1","JCRName":"Medicine","Score":null,"Total":0}

引用次数: 0

Abstract

Background

Ozone therapy is a rather novel approach for managing many diseases, encompassing oral disorders such as tooth caries and periodontal disease. It possesses the ability to disrupt microbial cell walls, resulting in rapid cell lysis. Moreover, characteristics of ozone such as anti-inflammation, stimulation and modulation of immunity contribute to mitigating the host response aspect of periodontal disease.

Objective

To assess the adjunctive advantages of irrigation of ozonized water in conjunction with mechanical debridement for the treatment of periodontitis.

Methodology

50 patients with chronic periodontitis and pocket probing depth ≥4 have been divided into 2 groups i.e. Test (n = 25) and control groups (n = 25). While the control group was administered normal saline irrigation and mechanical debridement, the test group was given ozonized water irrigation. Evaluations were conducted at baseline and four weeks following treatment to determine the plaque score, bleeding score, pocket probing depth, and clinical attachment level.

Results

Clinical measures such as clinical attachment level, pocket probing depth, bleeding index, and plaque index, significantly improved with adjunctive ozone water irrigation. The frequency of sites with bleeding on probing that had a pocket depth ≥4 mm was significantly reduced as a result of ozone water irrigation.

Conclusion

Ozone irrigation alongside nonsurgical periodontal therapy offers adjunctive benefits by reducing clinical parameters.

Abstract Image

查看原文本刊更多论文

求助全文

约1分钟内获得全文求助全文

来源期刊

Journal of oral biology and craniofacial research Medicine-Otorhinolaryngology

CiteScore

4.90

自引率

0.00%

发文量

133

审稿时长

167 days

期刊介绍： Journal of Oral Biology and Craniofacial Research (JOBCR)is the official journal of the Craniofacial Research Foundation (CRF). The journal aims to provide a common platform for both clinical and translational research and to promote interdisciplinary sciences in craniofacial region. JOBCR publishes content that includes diseases, injuries and defects in the head, neck, face, jaws and the hard and soft tissues of the mouth and jaws and face region; diagnosis and medical management of diseases specific to the orofacial tissues and of oral manifestations of systemic diseases; studies on identifying populations at risk of oral disease or in need of specific care, and comparing regional, environmental, social, and access similarities and differences in dental care between populations; diseases of the mouth and related structures like salivary glands, temporomandibular joints, facial muscles and perioral skin; biomedical engineering, tissue engineering and stem cells. The journal publishes reviews, commentaries, peer-reviewed original research articles, short communication, and case reports.