{"title":"Monitoring of hepatitis B infection in the elderly population of eastern Iran","authors":"Abdol Sattar Pagheh , Effat Alemzadeh , Eisa Nazar , Mitra Moodi , Farshad Sharifi , Ebrahim Miri-Moghaddam , Mohamad Taghi Rahimi , Soroush Mohammadi , Masood Ziaee","doi":"10.1016/j.vacune.2025.100373","DOIUrl":null,"url":null,"abstract":"<div><h3>Objectives</h3><div>This study aimed to investigate the prevalence of HBV infection and its associated risk factors in the elderly in Birjand.</div></div><div><h3>Materials and methods</h3><div>The present study was a part of the community-based prospective cohort study. Subjects over 60 years of age were assessed using standard questionnaires and blood factors. The samples were tested for HBsAg by enzyme-linked immunosorbent assay.</div></div><div><h3>Results</h3><div>Of 542 elderly people living in Birjand, 11 cases (2.03%) were positive. The median age of patients with HBsAg positive and negative was 69 (IQR: 63–77) years and 67 (IQR: 63–74) years, respectively. The results of the multiple logistic regression model showed that fatty liver disease was significantly associated with having hepatitis B (AOR (95% CI)=5.50 (1.16, 25.88)) (<em>p</em> <!--><<!--> <!-->.05). However, there was no significant relationship found between variables age, sex, marital status, years of study, underlying diseases, body mass index, smoking, and blood factors with having hepatitis B (<em>p</em> <!-->><!--> <!-->.05).</div></div><div><h3>Conclusions</h3><div>Even though there were only a few positive cases, leading to a non-significant report, it is crucial to emphasize the clinical significance and health and well-being of elderly individuals contracting hepatitis B. This information can be valuable in devising suitable disease management strategies for this age group.</div></div>","PeriodicalId":101272,"journal":{"name":"Vacunas (English Edition)","volume":"26 1","pages":"Article 100373"},"PeriodicalIF":0.0000,"publicationDate":"2025-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":"0","resultStr":null,"platform":"Semanticscholar","paperid":null,"PeriodicalName":"Vacunas (English Edition)","FirstCategoryId":"1085","ListUrlMain":"https://www.sciencedirect.com/science/article/pii/S2445146025000044","RegionNum":0,"RegionCategory":null,"ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":null,"EPubDate":"","PubModel":"","JCR":"","JCRName":"","Score":null,"Total":0}
引用次数: 0
Abstract
Objectives
This study aimed to investigate the prevalence of HBV infection and its associated risk factors in the elderly in Birjand.
Materials and methods
The present study was a part of the community-based prospective cohort study. Subjects over 60 years of age were assessed using standard questionnaires and blood factors. The samples were tested for HBsAg by enzyme-linked immunosorbent assay.
Results
Of 542 elderly people living in Birjand, 11 cases (2.03%) were positive. The median age of patients with HBsAg positive and negative was 69 (IQR: 63–77) years and 67 (IQR: 63–74) years, respectively. The results of the multiple logistic regression model showed that fatty liver disease was significantly associated with having hepatitis B (AOR (95% CI)=5.50 (1.16, 25.88)) (p < .05). However, there was no significant relationship found between variables age, sex, marital status, years of study, underlying diseases, body mass index, smoking, and blood factors with having hepatitis B (p > .05).
Conclusions
Even though there were only a few positive cases, leading to a non-significant report, it is crucial to emphasize the clinical significance and health and well-being of elderly individuals contracting hepatitis B. This information can be valuable in devising suitable disease management strategies for this age group.