Retrospective Evaluation of the Correlation Between PaO2:FiO2 and SpO2:FiO2 Ratios in Dogs Undergoing High-Flow Nasal Cannula Oxygen Therapy

IF 1.2 3区农林科学 Q3 VETERINARY SCIENCES

Journal of veterinary emergency and critical care Pub Date : 2025-03-28 DOI:10.1111/vec.13463

Jiwoong Her, Emily Lu, Kendon Kuo

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引用次数: 0

Abstract

Background

In veterinary medicine, high-flow nasal cannula oxygen therapy (HFNT) has gained popularity in managing hypoxemic respiratory failure, bridging the gap between conventional oxygen therapy and mechanical ventilation. The SpO₂:FiO₂ (SF) ratio could be useful in assessing oxygenation impairment in dogs undergoing HFNT. The current study aimed to determine whether the SF ratio correlates with the PaO₂:FiO₂ (PF) ratio in dogs undergoing HFNT.

Key Findings

A total of 30 data pairs with concurrent SpO₂ and PaO₂ measurements were identified from 19 dogs treated with HFNT from two university veterinary teaching hospitals. PF and SF ratios were measured when PaO₂ fell between 74 and 129 mm Hg. The median SF and PF ratios were 186 (interquartile range: 97–243) and 168 (interquartile range: 108–297), respectively. SF ratios were strongly correlated with PF ratios (rho = 0.86 [95% confidence interval: 0.73–0.93], p < 0.001, weighted r = 0.89 [95% confidence interval: 0.74–0.96]).

Significance

Preliminary results suggest a statistically significant positive correlation between SF and PF ratios in dogs treated with HFNT. This study provides data that can be used to calculate appropriate sample sizes for subsequent studies investigating the specific SF ratios corresponding with the PF ratios as the criteria for assessing hypoxemia.

Abstract Image

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对接受高流量鼻导管供氧疗法的狗的 Pa2:FiO2 和 SpO2 比率之间的相关性进行回顾性评估。

背景：在兽医学中，高流量鼻插管氧疗（HFNT）在治疗低氧血症性呼吸衰竭方面越来越受欢迎，弥补了传统氧疗和机械通气之间的差距。SpO2:FiO2 （SF）比值可用于评估HFNT犬的氧合损伤。本研究旨在确定接受HFNT的狗的SF比率是否与PaO2:FiO2 （PF）比率相关。主要发现：从两所大学兽医教学医院接受HFNT治疗的19只狗中共鉴定出30对SpO2和PaO2同时测量的数据。当PaO2降至74 ~ 129 mm Hg时，测定PF和SF比值，SF和PF比值中位数分别为186（四分位数范围为97 ~ 243）和168（四分位数范围为108 ~ 297）。SF比率与PF比率呈强相关(rho = 0.86[95%可信区间：0.73-0.93]，P显著性：初步结果显示HFNT治疗犬SF和PF比率呈正相关，具有统计学意义。本研究提供的数据可用于计算合适的样本量，为后续研究提供相应的SF比率作为评估低氧血症的标准。

本文章由计算机程序翻译，如有差异，请以英文原文为准。

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来源期刊

Journal of veterinary emergency and critical care 农林科学-兽医学

CiteScore

2.50

自引率

15.40%

发文量

121

审稿时长

18-36 weeks

期刊介绍： The Journal of Veterinary Emergency and Critical Care’s primary aim is to advance the international clinical standard of care for emergency/critical care patients of all species. The journal’s content is relevant to specialist and non-specialist veterinarians practicing emergency/critical care medicine. The journal achieves it aims by publishing descriptions of unique presentation or management; retrospective and prospective evaluations of prognosis, novel diagnosis, or therapy; translational basic science studies with clinical relevance; in depth reviews of pertinent topics; topical news and letters; and regular themed issues. The journal is the official publication of the Veterinary Emergency and Critical Care Society, the American College of Veterinary Emergency and Critical Care, the European Veterinary Emergency and Critical Care Society, and the European College of Veterinary Emergency and Critical Care. It is a bimonthly publication with international impact and adheres to currently accepted ethical standards.