Tarik El Ghalbzouri , Tarek El Bardouni , Jaafar El Bakkali , Mohamed Drissi El-Bouzaidi , Hicham Satti
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引用次数: 0
Abstract
Internal radiation dosimetry is critical in nuclear medicine procedures involving radiopharmaceuticals as it evaluates the risks and benefits of diagnostic and therapeutic applications. In this context, radiological protection quantities, including absorbed dose and effective dose, are derived from the specific absorbed fraction (SAF), a fundamental dose coefficient. The SAF quantifies the fraction of energy deposited in a target region per unit mass relative to the energy emitted from a specified source region.
Updating the SAF dataset using the latest mesh-type computational phantoms is strongly recommended. Comparing these values with SAFs from earlier voxel-based phantoms helps identify targetsource combinations with variations in internal dosimetry coefficients, reflecting the anatomical improvements in mesh-type phantoms.
Simulations using the DoseCalcs platform were conducted for electron and photon transport at eight energies (10 keV to 2 MeV), employing the adult female mesh-type phantom from ICRP Publication 145. Subsequently, SAFs were calculated for twenty-four distinct source regions and compared with those derived by OpenDose using the voxel-based model.
The results showed that SAFs calculated with mesh-type and voxel-based phantoms are similar, with minor differences observed for both photons and electrons. Notable variations were observed for photons in the spleenliver combination and for electrons at low energy, particularly in the pancreasliver and liverpancreas combinations. These differences highlight the impact of anatomical improvements in mesh-type phantoms. These differences arise from improved internal structures, particularly for adjacent organs/tissues, due to differences in contact surface geometry. The mesh-type model uses smooth surfaces, while the voxel-based model employs stair-based surfaces.
期刊介绍:
Radiation Physics and Chemistry is a multidisciplinary journal that provides a medium for publication of substantial and original papers, reviews, and short communications which focus on research and developments involving ionizing radiation in radiation physics, radiation chemistry and radiation processing.
The journal aims to publish papers with significance to an international audience, containing substantial novelty and scientific impact. The Editors reserve the rights to reject, with or without external review, papers that do not meet these criteria. This could include papers that are very similar to previous publications, only with changed target substrates, employed materials, analyzed sites and experimental methods, report results without presenting new insights and/or hypothesis testing, or do not focus on the radiation effects.