Characteristics and Outcomes of Patients Admitted for Diabetic Foot Attack.

Federico Rolando Bonanni, Marco Meloni, Martina Salvi, Ermanno Bellizzi, Valeria Ruotolo, Aikaterini Andreadi, Alfonso Bellia, Davide Lauro
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Abstract

The current study aimed to evaluate characteristics and outcomes of patients admitted for a diabetic foot attack (DFA). It is a retrospective observational study including a population of patients admitted for diabetic foot ulcers (DFU) in a specialized diabetic foot service. Based on the type of hospital admission (emergency or elective), patients were divided into two groups: those with DFA and those without DFA (chronic diabetic foot, CDF). The DFA was considered in case of ischemia, infection and Charcot foot requiring urgent hospitalization. The following in-hospital outcomes were evaluated: minor and major amputation, number of surgical procedures, length of stay (LOS), mortality. Overall, 150 patients were included. The mean age was 70.3 ± 12.2 years, most patients were male (76.0%) and had type 2 diabetes (92.7%) with a mean duration of 22.1 ± 13.2 years; 88 (58.7%) patients presented DFA while 62 (41.3%) presented CDF. The DFA group reported a greater rate of foot infection (81.8 vs 50.0%, p = 0.002), higher HbA1c values (67.9 ± 22 vs 56.6 ± 14.3 mmol/mol, p = 0.0005) and more cases of first assessment for DFUs (43.2 vs 12.9%, p = 0.005) compared with the CDF group. Outcomes for DFA and CDF were minor amputation (36.4 vs 21%, p = 0.04), major amputation (2.3 vs 1.6%, p = 0.7), need for surgical procedures (>1) (27.3 vs 11.3%, p = 0.0001), LOS (17 ± 9.6 vs 12 ± 6.3 days, p = 0.0004), mortality (1.1 vs 0%, p = 0.6). In addition, foot infection and poor glycometabolic control were independently related to the DFA presentation. The DFA increases the risk of minor amputations, more surgical procedures and longer hospitalization. Foot infection and poor metabolic control resulted closely related to the DFA.

糖尿病足发作入院患者的特征和疗效
本研究旨在评估因糖尿病足发作(DFA)而入院的患者的特征和治疗效果。这是一项回顾性观察研究,研究对象包括在糖尿病足专科医院接受治疗的糖尿病足溃疡(DFU)患者。根据入院类型(急诊或择期入院),患者被分为两组:DFA患者和无DFA患者(慢性糖尿病足,CDF)。缺血、感染和需要紧急入院治疗的夏科病足患者才考虑使用 DFA。对以下院内结果进行了评估:轻度和重度截肢、手术次数、住院时间(LOS)、死亡率。共纳入 150 名患者。平均年龄为 70.3 ± 12.2 岁,大多数患者为男性(76.0%),2 型糖尿病患者(92.7%),平均病程为 22.1 ± 13.2 年;88 名患者(58.7%)为 DFA,62 名患者(41.3%)为 CDF。与 CDF 组相比,DFA 组足部感染率更高(81.8 vs 50.0%,p = 0.002),HbA1c 值更高(67.9 ± 22 vs 56.6 ± 14.3 mmol/mol,p = 0.0005),首次评估为 DFUs 的病例更多(43.2 vs 12.9%,p = 0.005)。DFA 组和 CDF 组的结果分别为轻度截肢(36.4 对 21%,p = 0.04)、重度截肢(2.3 对 1.6%,p = 0.7)、需要外科手术(>1)(27.3 对 11.3%,p = 0.0001)、LOS(17 ± 9.6 对 12 ± 6.3 天,p = 0.0004)、死亡率(1.1 对 0%,p = 0.6)。此外,足部感染和糖代谢控制不佳也与 DFA 表现独立相关。DFA 增加了轻微截肢、更多外科手术和更长时间住院的风险。足部感染和代谢控制不良与 DFA 密切相关。
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