Carbapenem-Resistant Pseudomonas aeruginosa from Guanay Cormorants on Is. Pescadores, Peru.

IF 2.2 3区环境科学与生态学 Q3 ENVIRONMENTAL SCIENCES

Ecohealth Pub Date : 2025-03-26 DOI:10.1007/s10393-025-01712-2

Luciano A Palomino-Kobayashi, Carlos Zavalaga, Cinthia Irigoin-Lovera, Diego Gonzales-DelCarpio, Rocío Egoávil-Espejo, Fernanda Borges-Barbosa, Maria J Pons, Joaquim Ruiz

引用次数: 0

Abstract

Five carbapenem-resistant P. aeruginosa isolates were obtained from 33 adult Guanay Cormorants from Isla Pescadores, Lima, Peru. Four isolates had a similar antibiotic susceptibility profile and their carbapenem resistance was attributed to mutations in OprD porin; whilst the last isolate carried both bla_VIM (encoded within a Class 1 integron) and bla_IMP. Moreover, the VIM/IMP co-producer belongs to ST111, considered as a high-risk clone. The other isolates could not be identified by MLST since amplification of mutL, aroE, and acsA could not be achieved. The exoA and exoT genes were present in all isolates, while the VIM/IMP isolate also carried exoS and exoY but neither exoU nor algD. BOX-PCR showed that the VIM/IMP isolate was not clonally related to the other four. These findings highlight the importance of surveillance and characterisation of carbapenem-resistant bacteria from environmental sources in Peru.

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来自瓜内鸬鹚的耐碳青霉烯铜绿假单胞菌。澎湖列岛、秘鲁。

从秘鲁利马澎湖岛（Isla Pescadores）的33只成年瓜奈鸬鹚体内分离出5株耐碳青霉烯类细菌。其中四个分离株具有相似的抗生素敏感性，其碳青霉烯类耐药性归因于 OprD 孔蛋白的突变；而最后一个分离株同时携带 blaVIM（在 1 类整合子中编码）和 blaIMP。此外，VIM/IMP 共同产生者属于 ST111，被认为是高风险克隆。由于无法扩增 mutL、aroE 和 acsA，因此无法通过 MLST 鉴定其他分离物。所有分离株都含有 exoA 和 exoT 基因，而 VIM/IMP 分离株还含有 exoS 和 exoY 基因，但不含 exoU 和 algD。BOX-PCR 显示，VIM/IMP 分离物与其他四个分离物没有克隆关系。这些发现凸显了对秘鲁环境来源的耐碳青霉烯类细菌进行监控和鉴定的重要性。

本文章由计算机程序翻译，如有差异，请以英文原文为准。

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来源期刊

Ecohealth 环境科学-环境科学

CiteScore

4.50

自引率

4.00%

发文量

审稿时长

>24 weeks

期刊介绍： EcoHealth aims to advance research, practice, and knowledge integration at the interface of ecology and health by publishing high quality research and review articles that address and profile new ideas, developments, and programs. The journal’s scope encompasses research that integrates concepts and theory from many fields of scholarship (including ecological, social and health sciences, and the humanities) and draws upon multiple types of knowledge, including those of relevance to practice and policy. Papers address integrated ecology and health challenges arising in public health, human and veterinary medicine, conservation and ecosystem management, rural and urban development and planning, and other fields that address the social-ecological context of health. The journal is a central platform for fulfilling the mission of the EcoHealth Alliance to strive for sustainable health of people, domestic animals, wildlife, and ecosystems by promoting discovery, understanding, and transdisciplinarity. The journal invites substantial contributions in the following areas: One Health and Conservation Medicine o Integrated research on health of humans, wildlife, livestock and ecosystems o Research and policy in ecology, public health, and agricultural sustainability o Emerging infectious diseases affecting people, wildlife, domestic animals, and plants o Research and practice linking human and animal health and/or social-ecological systems o Anthropogenic environmental change and drivers of disease emergence in humans, wildlife, livestock and ecosystems o Health of humans and animals in relation to terrestrial, freshwater, and marine ecosystems Ecosystem Approaches to Health o Systems thinking and social-ecological systems in relation to health o Transdiiplinary approaches to health, ecosystems and society.