Sedigheh Reisian, Shokoufeh Bonakdaran, Ali Moradi, Mohammad Ali Yaghoubi
{"title":"Teriparatide-induced Sever Persistent Hypercalcemia in an Osteoporotic Patient: A Case Report and Literature Review.","authors":"Sedigheh Reisian, Shokoufeh Bonakdaran, Ali Moradi, Mohammad Ali Yaghoubi","doi":"10.22038/ABJS.2024.80907.3690","DOIUrl":null,"url":null,"abstract":"<p><p>A rare case of severe prolonged persistent Teriparatide-induced hypercalcemia (14.3mg/dL on admission) in an osteoporotic patient after ceasing the Teriparatide is reported. This 67-year-old female was admitted with polyuria, xerostomia, constipation, progressive weakness, and a history of Triparatide use due to a previous osteoporotic fracture. Her serum calcium, PTH, and vitamin D levels had been normal before starting Teriparatide. Ninety six hours after ceasing the Teriparatide along with rehydration and Calcitonin treatment, the patient's serum calcium levels returned to normal. Severe Teriparatide-induced hypercalcemia does not follow any defined pattern and may persist for days and can usually be controlled through ceasing the Teriparatide, rehydration, and close monitoring of the serum calcium level and symptoms.</p>","PeriodicalId":46704,"journal":{"name":"Archives of Bone and Joint Surgery-ABJS","volume":"13 3","pages":"170-175"},"PeriodicalIF":1.2000,"publicationDate":"2025-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11938360/pdf/","citationCount":"0","resultStr":null,"platform":"Semanticscholar","paperid":null,"PeriodicalName":"Archives of Bone and Joint Surgery-ABJS","FirstCategoryId":"1085","ListUrlMain":"https://doi.org/10.22038/ABJS.2024.80907.3690","RegionNum":0,"RegionCategory":null,"ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":null,"EPubDate":"","PubModel":"","JCR":"Q3","JCRName":"ORTHOPEDICS","Score":null,"Total":0}
引用次数: 0
Abstract
A rare case of severe prolonged persistent Teriparatide-induced hypercalcemia (14.3mg/dL on admission) in an osteoporotic patient after ceasing the Teriparatide is reported. This 67-year-old female was admitted with polyuria, xerostomia, constipation, progressive weakness, and a history of Triparatide use due to a previous osteoporotic fracture. Her serum calcium, PTH, and vitamin D levels had been normal before starting Teriparatide. Ninety six hours after ceasing the Teriparatide along with rehydration and Calcitonin treatment, the patient's serum calcium levels returned to normal. Severe Teriparatide-induced hypercalcemia does not follow any defined pattern and may persist for days and can usually be controlled through ceasing the Teriparatide, rehydration, and close monitoring of the serum calcium level and symptoms.
期刊介绍：
The Archives of Bone and Joint Surgery (ABJS) aims to encourage a better understanding of all aspects of Orthopedic Sciences. The journal accepts scientific papers including original research, review article, short communication, case report, and letter to the editor in all fields of bone, joint, musculoskeletal surgery and related researches. The Archives of Bone and Joint Surgery (ABJS) will publish papers in all aspects of today`s modern orthopedic sciences including: Arthroscopy, Arthroplasty, Sport Medicine, Reconstruction, Hand and Upper Extremity, Pediatric Orthopedics, Spine, Trauma, Foot and Ankle, Tumor, Joint Rheumatic Disease, Skeletal Imaging, Orthopedic Physical Therapy, Rehabilitation, Orthopedic Basic Sciences (Biomechanics, Biotechnology, Biomaterial..).
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