The contribution of dietary total antioxidant capacity to type 2 diabetes risk and levels of glycemic biomarkers: a systematic review.

IF 2.1 Q3 PUBLIC, ENVIRONMENTAL & OCCUPATIONAL HEALTH
Sorayya Kheirouri, Hamed Alizadeh
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引用次数: 0

Abstract

Objectives: This study systematically reviewed and analyzed epidemiological evidence regarding the association between dietary total antioxidant capacity (DTAC) and both the risk of developing diabetes and glycemic biomarker levels.

Methods: We searched the PubMed, Scopus, ScienceDirect, and Google Scholar databases through July 2024 without imposing any date restrictions. Original studies that examined the relationship between DTAC and either the risk of developing diabetes or glycemic biomarker levels-specifically fasting blood glucose (FBG), hemoglobin A1C (HbA1C), insulin, and the homeostatic model assessment for insulin resistance (HOMA-IR)-were eligible for inclusion. After eliminating duplicates and irrelevant records, relevant studies were selected, and data were extracted through rigorous critical analysis.

Results: A total of 32 articles were included in the review. Of the 19 studies that evaluated diabetes risk, 15 reported a lower risk among subjects with higher DTAC values. All 4 studies examining prediabetes risk found lower risk in participants with high DTAC scores. Additionally, significant inverse relationships were observed between DTAC values and FBG (9/15 studies), HbA1C (1/6 studies), insulin (5/6 studies), and HOMA-IR (8/9 studies).

Conclusion: The majority of evidence indicates that high adherence to an antioxidant-rich diet may reduce diabetes risk and improve glycemic biomarkers, including FBG, insulin, and HOMA-IR.

膳食总抗氧化能力对2型糖尿病风险和血糖生物标志物水平的贡献:一项系统综述
目的:本研究系统回顾和分析了膳食总抗氧化能力(DTAC)与糖尿病发病风险和血糖生物标志物水平之间关系的流行病学证据。方法:我们检索了PubMed、Scopus、ScienceDirect和谷歌Scholar数据库,截止到2024年7月,没有任何日期限制。检查DTAC与糖尿病风险或血糖生物标志物水平(特别是空腹血糖(FBG)、血红蛋白A1C (HbA1C)、胰岛素和胰岛素抵抗的稳态模型评估(HOMA-IR))之间关系的原始研究符合纳入条件。在剔除重复和不相关的记录后,选择相关的研究,并通过严格的批判性分析提取数据。结果:共纳入32篇文献。在19项评估糖尿病风险的研究中,15项报告了DTAC值较高的受试者患糖尿病的风险较低。所有4项检查糖尿病前期风险的研究都发现DTAC得分高的参与者风险较低。此外,DTAC值与FBG(9/15项研究)、HbA1C(1/6项研究)、胰岛素(5/6项研究)和HOMA-IR(8/9项研究)之间存在显著的负相关。结论:大多数证据表明,高度坚持富含抗氧化剂的饮食可以降低糖尿病风险,改善血糖生物标志物,包括FBG、胰岛素和HOMA-IR。
本文章由计算机程序翻译,如有差异,请以英文原文为准。
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来源期刊
Osong Public Health and Research Perspectives
Osong Public Health and Research Perspectives Medicine-Public Health, Environmental and Occupational Health
CiteScore
10.30
自引率
2.30%
发文量
44
审稿时长
16 weeks
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