[Fertility treatment of men with Klinefelter syndrome].

Q4 Medicine

Ugeskrift for laeger Pub Date : 2025-03-17 DOI:10.61409/V10240694

Jens Fedder, Anne Skakkebæk, Christan Fuglesang S Jensen, Claus H Gravholt

引用次数: 0

Abstract

In this review is described, that men with Klinefelter syndrome (KS) usually have azoospermia, and only a few have obtained paternity with ejaculated sperm. In Denmark, we performed surgery (micro-TESE or subcapsular orchiectomy) in 93 men with KS and obtained testicular sperm in 42% (39). More than ten children are now born, and several couples still have sperm and embryos cryopreserved with the potential to increase the live birth rate further. Since sperm in men with KS originate from cell lines with a normal chromosome number, children born with a father with KS usually have a normal karyotype and are healthy.

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[克氏综合征男性的生育治疗]。

本文介绍了Klinefelter综合征（KS）的男性通常有无精子症，只有少数人获得了射精精子。在丹麦，我们对93名患有KS的男性进行了手术（微睾丸切除术或包膜下睾丸切除术），其中42%（39）获得了睾丸精子。现在已经有十多个孩子出生了，还有几对夫妇仍然冷冻保存精子和胚胎，以进一步提高活产率。由于患有KS的男性的精子来源于染色体数目正常的细胞系，因此患有KS的父亲所生的孩子通常具有正常的核型并且是健康的。

本文章由计算机程序翻译，如有差异，请以英文原文为准。

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来源期刊

Ugeskrift for laeger Medicine-Medicine (all)

CiteScore

0.20

自引率

0.00%

发文量

345

期刊介绍： The Ulster Medical Journal is an international general medical journal with contributions on all areas of medical and surgical specialties relevant to a general medical readership. It retains a focus on material relevant to the health of the Northern Ireland population. The Honorary Editor would welcome offers of papers for publication. Prospective authors are invited to read the notice to contributors.