Biomonitoring of Serum Inorganic Element Concentrations in Morbidly Obese Patients: Impact of Bariatric Surgery.

IF 3.9 3区环境科学与生态学 Q2 ENVIRONMENTAL SCIENCES

Toxics Pub Date : 2025-02-23 DOI:10.3390/toxics13030152

Álvaro Ramos-Luzardo, Pilar Fernández Valerón, Beatriz Vanessa Díaz-González, Manuel Zumbado, Katherine Simbaña-Rivera, Inmaculada Bautista-Castaño, Norberto Ruiz-Suárez, Elisabeth Hernández-García, Judith Cornejo-Torre, Octavio P Luzardo, Lluis Serra-Majem, Luis Alberto Henríquez-Hernández

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引用次数: 0

Abstract

Adipose tissue, in addition to serving as energy storage, can store lipophilic substances, some of which may pose a health risk if massively mobilized during rapid weight loss. This study aimed to biomonitor inorganic elements in obese patients undergoing bariatric surgery and analyze the role of sociodemographic factors. ICP-MS was employed to quantify 55 elements, including elements identified from the ATSDR's Substance Priority List and rare-earth elements, in serum samples of 58 obese patients before and after bariatric surgery. A total of 39 out of 55 elements were detected, either before or after surgery, in at least one patient. Serum concentrations of gold, copper, mercury, platinum, and selenium significantly decreased after surgery. Serum concentrations of iron and zinc were significantly lower before surgery. Age, sex, diabetes status, arterial hypertension, and family history of obesity were demographic factors associated with the concentration of elements. Correlation analyses showed significant associations between elements and total lipid concentration or body mass index. Our findings indicate a complex interplay between inorganic elements and body fat and provide relevant information regarding the biomonitoring of these chemical elements in a specific and understudied population.

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来源期刊

Toxics Chemical Engineering-Chemical Health and Safety

CiteScore

4.50

自引率

10.90%

发文量

681

审稿时长

6 weeks

期刊介绍： Toxics (ISSN 2305-6304) is an international, peer-reviewed, open access journal which provides an advanced forum for studies related to all aspects of toxic chemicals and materials. It publishes reviews, regular research papers, and short communications. Our aim is to encourage scientists to publish their experimental and theoretical results in detail. There is, therefore, no restriction on the maximum length of the papers, although authors should write their papers in a clear and concise way. The full experimental details must be provided so that the results can be reproduced. Electronic files or software regarding the full details of calculations and experimental procedure can be deposited as supplementary material, if it is not possible to publish them along with the text.