Wheezing Episodes in Children Before and After the Onset of the COVID-19 Pandemic in Brussels.

IF 2.7 3区医学 Q1 PEDIATRICS

Pediatric Pulmonology Pub Date : 2025-04-01 DOI:10.1002/ppul.71068

Clementine Delporte, Lore Van Bruwaene, Nicolas Bruffaerts, Elisabeth Rebuffat, Tessa Goetghebuer

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引用次数: 0

Abstract

Purpose: Studies have demonstrated important changes in the seasonality of pediatric respiratory illnesses since the onset of the COVID-19 pandemic. The aim of this study was to describe the epidemiology of childhood wheezing episodes before and after the start of the COVID-19 pandemic in relation to their potentially associated environmental triggers.

Methods: Files of all children treated with salbutamol for an acute wheezing episode in September and October 2019, 2020, and 2021 were retrospectively reviewed. Infection epidemiology, daily concentrations of air pollutants (NO₂, O₃, PM₁₀, and PM_2.5), and fungal spores were collected over the same time period.

Results: In 2021, 298 episodes of wheezing were observed compared to 111 in 2020 and 86 in 2019 (p < 0.001). Compared to 2019, children with wheezing in 2021 were significantly older (p < 0.001), less likely to have a history of recurrent wheezing (p < 0.001) and required less hospitalization (p = 0.034). Adenovirus and SARS-CoV-2 were more prevalent in 2021 as compared to 2019 (p < 0.001). The concentration of PM₁₀, PM_2.5, and O₃ was higher in 2021, as compared to both 2019 and 2020 (p < 0.001) while the concentration of NO₂ and airborne spores was lower in 2021 compared to 2019 (p < 0.0001).

Conclusion: A threefold increase in wheezing episodes was observed in the autumn post-COVID (2021) compared to pre-COVID (2019) together with very high circulation of SARS-CoV-2 and a significant increase of PM₁₀, PM_2.5, and O_3.

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布鲁塞尔2019冠状病毒病大流行前后儿童喘息发作情况

目的：研究表明，自COVID-19大流行爆发以来，儿科呼吸系统疾病的季节性发生了重要变化。本研究的目的是描述COVID-19大流行开始前后儿童喘息发作的流行病学与潜在相关环境触发因素的关系。方法：回顾性分析2019年9月和10月、2020年和2021年使用沙丁胺醇治疗急性喘息发作的所有儿童的档案。收集同一时间段的感染流行病学、空气污染物（NO2、O3、PM10和PM2.5）的日浓度以及真菌孢子。结果:2021年,298集的喘息观察比111年2019年2020年和86年(p 10、PM2.5和O3在2021年高,相比2019年和2020年(p 2和空中孢子是较低的2021年相比,2019年(p结论:观察气喘发作增加三倍,在秋季post-COVID pre-COVID相比(2021)(2019)和高循环SARS-CoV-2和PM10的显著增加,PM2.5,和O3。

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来源期刊

Pediatric Pulmonology 医学-呼吸系统

CiteScore

6.00

自引率

12.90%

发文量

468

审稿时长

3-8 weeks

期刊介绍： Pediatric Pulmonology (PPUL) is the foremost global journal studying the respiratory system in disease and in health as it develops from intrauterine life though adolescence to adulthood. Combining explicit and informative analysis of clinical as well as basic scientific research, PPUL provides a look at the many facets of respiratory system disorders in infants and children, ranging from pathological anatomy, developmental issues, and pathophysiology to infectious disease, asthma, cystic fibrosis, and airborne toxins. Focused attention is given to the reporting of diagnostic and therapeutic methods for neonates, preschool children, and adolescents, the enduring effects of childhood respiratory diseases, and newly described infectious diseases. PPUL concentrates on subject matters of crucial interest to specialists preparing for the Pediatric Subspecialty Examinations in the United States and other countries. With its attentive coverage and extensive clinical data, this journal is a principle source for pediatricians in practice and in training and a must have for all pediatric pulmonologists.