Postoperative Outcomes and Prognostic Factors of High Myopia Epiretinal Membrane Associated with Retinoschisis After Vitrectomy.

IF 2 4区医学 Q2 OPHTHALMOLOGY

Ophthalmic Research Pub Date : 2025-03-26 DOI:10.1159/000544928

Xiao Feng, Xiaohan Yang, Biying Qi, Xinbo Wang, Xijin Wu, Qinlang Jia, Wu Liu

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引用次数: 0

Abstract

Introduction: The outcomes and prognosis of pars plana vitrectomy (PPV) for high myopia epiretinal membranes (HM-ERM) patients with retinoschisis remains unclear. To analyze the impact of retinoschisis on the recovery of macular configuration and visual acuity following ERM removal in eyes with HM and to explore the prognostic factors.

Methods: A retrospective study of 73 consecutive patients with HM-ERM who underwent PPV with ERM peeling. According to the optical coherence tomography images, eyes were classified into 4 groups: group A without retinoschisis, group B with outer retinoschisis, group C with inner retinoschisis, group D with both inner and outer retinoschisis.

Results: In Groups A, B, C, and D, there were 17, 21, 22, and 16 eyes, respectively. Retinoschisis of 44 eyes (74.6%) disappeared postoperatively, including 13 eyes in group B, 20 in group C, and 9 in group D. A significant difference in the resolution of retinoschisis was observed between Groups C and D (P=0.036). No correlation was found between retinoschisis resolution and baseline factors. The mean best-corrected visual acuity (BCVA) significantly improved at the final follow-up (P＜0.001). The final BCVA was associated with baseline BCVA (P=0.007), the presence of epiretinal proliferation preoperatively (P=0.008) , and ithe postoperative integrity of the ellipsoid zone (EZ) (P<0.001) and interdigitation zone (IZ) (P=0.001).

Conclusions: After surgery, the inner retinoschisis usually resolved completely. Retinoschisis was not the main factor influencing final BCVA. Preoperative BCVA and disruption of EZ and IZ were associated with good visual recovery in long-term follow-up.

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来源期刊

Ophthalmic Research 医学-眼科学

CiteScore

3.80

自引率

4.80%

发文量

审稿时长

6-12 weeks

期刊介绍： ''Ophthalmic Research'' features original papers and reviews reporting on translational and clinical studies. Authors from throughout the world cover research topics on every field in connection with physical, physiologic, pharmacological, biochemical and molecular biological aspects of ophthalmology. This journal also aims to provide a record of international clinical research for both researchers and clinicians in ophthalmology. Finally, the transfer of information from fundamental research to clinical research and clinical practice is particularly welcome.