Outcomes After Silicone Oil Removal in Patients with Acute Retinal Necrosis Who Underwent Vitrectomy.

IF 2.6 4区医学 Q2 OPHTHALMOLOGY

Ocular Immunology and Inflammation Pub Date : 2025-07-01 Epub Date: 2025-03-27 DOI:10.1080/09273948.2025.2477193

Boya Lei, Xin Chen, Min Zhou, Ting Zhang, Ruiping Gu, Qinmeng Shu, Qing Chang, Gezhi Xu, Rui Jiang

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引用次数: 0

Abstract

Purpose: To investigate the outcomes after silicone oil removal (SOR) in patients with acute retinal necrosis (ARN).

Methods: Retrospective case series. Patients diagnosed with ARN-associated retinal detachment (RD) who underwent vitrectomy and silicone oil tamponade and subsequent SOR between January 2013 and December 2021 who were followed up for ≥1 year after SOR were included. The medical records before and after SOR were reviewed.

Results: Fifty-three eyes from 52 patients were included. SOR was conducted at 201.3 ± 104.1 days (range, 63‒547) after vitrectomy. The duration of follow-up after SOR was 1266.8 ± 797.2 days (range, 384-3865). The logMAR BCVA before SOR, at 1 year after SOR, and at the last follow-up were 1.249 ± 0.816, 1.086 ± 0.791, and 1.488 ± 0.961. The intraocular pressure (IOP) at the corresponding times were 13.2 ± 3.6, 10.9 ± 3.4, and 10.4 ± 3.5 mmHg. Seven patients (13.5%) experienced recurrent RD at 81.0 ± 46.7 days (range, 18‒154) after SOR. At 1 year after SOR, 4 eyes (7.5%) had hypotony and 26 (49.1%) had macular edema; the corresponding numbers were 7 (13.5%) and 27 (51.9%) at the last follow-up. The IOP at the time of SOR (r = -0.438, p = 0.001) was the risk factor for the occurrence of hypotony after SOR (area under the ROC curve: 0.873; cutoff value: 11.30 mmHg).

Conclusion: The BCVA and IOP continued to change after SOR in ARN patients. Ocular complications mostly occurred within the first year after SOR. IOP at the time of SOR was a main predictor of the clinical outcomes after SOR.

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玻璃体切除术后急性视网膜坏死患者硅油去除后的疗效。

目的：探讨硅油去除术（SOR）治疗急性视网膜坏死（ARN）的疗效。方法：回顾性病例系列。在2013年1月至2021年12月期间接受玻璃体切除术和硅油填塞并随后进行SOR的诊断为arn相关性视网膜脱离（RD）的患者在SOR后随访≥1年。回顾SOR前后的医疗记录。结果：纳入52例患者53只眼。在玻璃体切除术后201.3±104.1天（范围63-547）进行SOR。SOR后随访时间为1266.8±797.2天（范围384-3865）。SOR前、SOR后1年和末次随访时的logMAR BCVA分别为1.249±0.816、1.086±0.791和1.488±0.961。眼内压（IOP）分别为13.2±3.6、10.9±3.4、10.4±3.5 mmHg。7例患者（13.5%）在SOR后81.0±46.7天（范围18-154天）复发RD。SOR术后1年，4只眼（7.5%）出现低斜视，26只眼（49.1%）出现黄斑水肿；末次随访时分别为7例（13.5%）和27例（51.9%）。SOR时的IOP （r = -0.438, p = 0.001）是SOR后低斜视发生的危险因素(ROC曲线下面积：0.873；截止值：11.30 mmHg)。结论：ARN患者在SOR后BCVA和IOP继续发生变化。眼部并发症多发生在SOR术后一年内。SOR时的IOP是SOR后临床结果的主要预测因子。

本文章由计算机程序翻译，如有差异，请以英文原文为准。

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来源期刊

Ocular Immunology and Inflammation 医学-眼科学

CiteScore

6.20

自引率

15.20%

发文量

285

审稿时长

6-12 weeks

期刊介绍： Ocular Immunology & Inflammation ranks 18 out of 59 in the Ophthalmology Category.Ocular Immunology and Inflammation is a peer-reviewed, scientific publication that welcomes the submission of original, previously unpublished manuscripts directed to ophthalmologists and vision scientists. Published bimonthly, the journal provides an international medium for basic and clinical research reports on the ocular inflammatory response and its control by the immune system. The journal publishes original research papers, case reports, reviews, letters to the editor, meeting abstracts, and invited editorials.